Deubiquitinating enzymes as oncotargets

by McClurg, Urszula L., Robson, Craig N.
Published in Oncotarget (2015)

Using induced pluripotent stem cells as a tool for modelling carcinogenesis

by Curry, Emma L, Moad, Mohammad, Robson, Craig N, Heer, Rakesh
Published in World J Stem Cells (2015)

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

by Gaughan, Luke, Logan, Ian R., Neal, David E., Robson, Craig N.
Published 2005

Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer

by Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Published in Sci Rep (2017)

Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription

by Halkidou, Kalipso, Logan, Ian R., Cook, Susan, Neal, David E., Robson, Craig N.
Published 2004

Inhibition of Ubiquitination and Stabilization of Human Ubiquitin E3 Ligase PIRH2 by Measles Virus Phosphoprotein

by Chen, Mingzhou, Cortay, Jean-Claude, Logan, Ian R., Sapountzi, Vasileia, Robson, Craig N., Gerlier, Denis
Published 2005

Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

by McClurg, Urszula L., Summerscales, Emma E., Harle, Victoria J., Gaughan, Luke, Robson, Craig N.
Published 2014

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer

by Jones, Dominic, Wade, Mark, Nakjang, Sirintra, Chaytor, Lewis, Grey, James, Robson, Craig N., Gaughan, Luke
Published in Oncotarget (2015)

p68/DdX5 Supports β-Catenin & RNAP II during Androgen Receptor Mediated Transcription in Prostate Cancer

by Clark, Emma L., Hadjimichael, Christiana, Temperley, Richard, Barnard, Amy, Fuller-Pace, Frances V., Robson, Craig N.
Published 2013

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer

by Wade, Mark A., Jones, Dominic, Wilson, Laura, Stockley, Jacqueline, Coffey, Kelly, Robson, Craig N., Gaughan, Luke
Published in Nucleic Acids Res (2015)

Human PIRH2 Enhances Androgen Receptor Signaling through Inhibition of Histone Deacetylase 1 and Is Overexpressed in Prostate Cancer

by Logan, Ian R., Gaughan, Luke, McCracken, Stuart R. C., Sapountzi, Vasileia, Leung, Hing Y., Robson, Craig N.
Published 2006

Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells

by Munkley, Jennifer, Lafferty, Nicholas P, Kalna, Gabriela, Robson, Craig N, Leung, Hing Y, Rajan, Prabhakar, Elliott, David J
Published in BMC Cancer (2015)

The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7

by Stockley, Jacqueline, Markert, Elke, Zhou, Yan, Robson, Craig N., Elliott, David J., Lindberg, Johan, Leung, Hing Y., Rajan, Prabhakar
Published in Sci Rep (2015)

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival

by McClurg, Urszula L., Azizyan, Mahsa, Dransfield, Daniel T., Namdev, Nivedita, Chit, Nay C.T.H., Nakjang, Sirintra, Robson, Craig N.
Published in Oncotarget (2018)

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

by Kounatidou, Evangelia, Nakjang, Sirintra, McCracken, Stuart R C, Dehm, Scott M, Robson, Craig N, Jones, Dominic, Gaughan, Luke
Published in Nucleic Acids Res (2019)

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation

by Munkley, Jennifer, Rajan, Prabhakar, Laferty, Nicholas P., Dalgliesh, Caroline, Jackson, Robert M., Robson, Craig N., Leung, Hing Y., Elliott, David J.
Published 2013

Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage

by Logan, Ian R., McNeill, Hesta V., Cook, Susan, Lu, Xiaohong, Meek, David W., Fuller-Pace, Frances V., Lunec, John, Robson, Craig N.
Published 2009

Deubiquitinating Enzyme Usp12 Is a Novel Co-activator of the Androgen Receptor

by Burska, Urszula L., Harle, Victoria J., Coffey, Kelly, Darby, Steven, Ramsey, Hollie, O'Neill, Daniel, Logan, Ian R., Gaughan, Luke, Robson, Craig N.
Published 2013

Nutlin-3 inhibits androgen receptor-driven c-FLIP expression, resulting in apoptosis of prostate cancer cells

by Logan, Ian R., McClurg, Urszula L., Jones, Dominic L., O'Neill, Daniel J., Shaheen, Fadhel S., Lunec, John, Gaughan, Luke, Robson, Craig N.
Published in Oncotarget (2016)

Human α(2)β(1) (HI) CD133(+VE) Epithelial Prostate Stem Cells Express Low Levels of Active Androgen Receptor

by Williamson, Stuart C., Hepburn, Anastasia C., Wilson, Laura, Coffey, Kelly, Ryan-Munden, Claudia A., Pal, Deepali, Leung, Hing Y., Robson, Craig N., Heer, Rakesh
Published 2012