Deubiquitinating enzymes as oncotargets

Autor McClurg, Urszula L., Robson, Craig N.
Vydáno v Oncotarget (2015)

Using induced pluripotent stem cells as a tool for modelling carcinogenesis

Autor Curry, Emma L, Moad, Mohammad, Robson, Craig N, Heer, Rakesh
Vydáno v World J Stem Cells (2015)

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

Autor Gaughan, Luke, Logan, Ian R., Neal, David E., Robson, Craig N.
Vydáno 2005

Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer

Autor Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Vydáno v Sci Rep (2017)

Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription

Autor Halkidou, Kalipso, Logan, Ian R., Cook, Susan, Neal, David E., Robson, Craig N.
Vydáno 2004

Inhibition of Ubiquitination and Stabilization of Human Ubiquitin E3 Ligase PIRH2 by Measles Virus Phosphoprotein

Autor Chen, Mingzhou, Cortay, Jean-Claude, Logan, Ian R., Sapountzi, Vasileia, Robson, Craig N., Gerlier, Denis
Vydáno 2005

Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

Autor McClurg, Urszula L., Summerscales, Emma E., Harle, Victoria J., Gaughan, Luke, Robson, Craig N.
Vydáno 2014

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer

Autor Jones, Dominic, Wade, Mark, Nakjang, Sirintra, Chaytor, Lewis, Grey, James, Robson, Craig N., Gaughan, Luke
Vydáno v Oncotarget (2015)

p68/DdX5 Supports β-Catenin & RNAP II during Androgen Receptor Mediated Transcription in Prostate Cancer

Autor Clark, Emma L., Hadjimichael, Christiana, Temperley, Richard, Barnard, Amy, Fuller-Pace, Frances V., Robson, Craig N.
Vydáno 2013

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer

Autor Wade, Mark A., Jones, Dominic, Wilson, Laura, Stockley, Jacqueline, Coffey, Kelly, Robson, Craig N., Gaughan, Luke
Vydáno v Nucleic Acids Res (2015)

Human PIRH2 Enhances Androgen Receptor Signaling through Inhibition of Histone Deacetylase 1 and Is Overexpressed in Prostate Cancer

Autor Logan, Ian R., Gaughan, Luke, McCracken, Stuart R. C., Sapountzi, Vasileia, Leung, Hing Y., Robson, Craig N.
Vydáno 2006

Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells

Autor Munkley, Jennifer, Lafferty, Nicholas P, Kalna, Gabriela, Robson, Craig N, Leung, Hing Y, Rajan, Prabhakar, Elliott, David J
Vydáno v BMC Cancer (2015)

The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7

Autor Stockley, Jacqueline, Markert, Elke, Zhou, Yan, Robson, Craig N., Elliott, David J., Lindberg, Johan, Leung, Hing Y., Rajan, Prabhakar
Vydáno v Sci Rep (2015)

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival

Autor McClurg, Urszula L., Azizyan, Mahsa, Dransfield, Daniel T., Namdev, Nivedita, Chit, Nay C.T.H., Nakjang, Sirintra, Robson, Craig N.
Vydáno v Oncotarget (2018)

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

Autor Kounatidou, Evangelia, Nakjang, Sirintra, McCracken, Stuart R C, Dehm, Scott M, Robson, Craig N, Jones, Dominic, Gaughan, Luke
Vydáno v Nucleic Acids Res (2019)

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation

Autor Munkley, Jennifer, Rajan, Prabhakar, Laferty, Nicholas P., Dalgliesh, Caroline, Jackson, Robert M., Robson, Craig N., Leung, Hing Y., Elliott, David J.
Vydáno 2013

Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage

Autor Logan, Ian R., McNeill, Hesta V., Cook, Susan, Lu, Xiaohong, Meek, David W., Fuller-Pace, Frances V., Lunec, John, Robson, Craig N.
Vydáno 2009

Deubiquitinating Enzyme Usp12 Is a Novel Co-activator of the Androgen Receptor

Autor Burska, Urszula L., Harle, Victoria J., Coffey, Kelly, Darby, Steven, Ramsey, Hollie, O'Neill, Daniel, Logan, Ian R., Gaughan, Luke, Robson, Craig N.
Vydáno 2013

Nutlin-3 inhibits androgen receptor-driven c-FLIP expression, resulting in apoptosis of prostate cancer cells

Autor Logan, Ian R., McClurg, Urszula L., Jones, Dominic L., O'Neill, Daniel J., Shaheen, Fadhel S., Lunec, John, Gaughan, Luke, Robson, Craig N.
Vydáno v Oncotarget (2016)

Human α(2)β(1) (HI) CD133(+VE) Epithelial Prostate Stem Cells Express Low Levels of Active Androgen Receptor

Autor Williamson, Stuart C., Hepburn, Anastasia C., Wilson, Laura, Coffey, Kelly, Ryan-Munden, Claudia A., Pal, Deepali, Leung, Hing Y., Robson, Craig N., Heer, Rakesh
Vydáno 2012