Deubiquitinating enzymes as oncotargets

per McClurg, Urszula L., Robson, Craig N.
Publicat a Oncotarget (2015)

Using induced pluripotent stem cells as a tool for modelling carcinogenesis

per Curry, Emma L, Moad, Mohammad, Robson, Craig N, Heer, Rakesh
Publicat a World J Stem Cells (2015)

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

per Gaughan, Luke, Logan, Ian R., Neal, David E., Robson, Craig N.
Publicat 2005

Aurora A regulates expression of AR-V7 in models of castrate resistant prostate cancer

per Jones, Dominic, Noble, Martin, Wedge, Steve R., Robson, Craig N., Gaughan, Luke
Publicat a Sci Rep (2017)

Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcription

per Halkidou, Kalipso, Logan, Ian R., Cook, Susan, Neal, David E., Robson, Craig N.
Publicat 2004

Inhibition of Ubiquitination and Stabilization of Human Ubiquitin E3 Ligase PIRH2 by Measles Virus Phosphoprotein

per Chen, Mingzhou, Cortay, Jean-Claude, Logan, Ian R., Sapountzi, Vasileia, Robson, Craig N., Gerlier, Denis
Publicat 2005

Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway

per McClurg, Urszula L., Summerscales, Emma E., Harle, Victoria J., Gaughan, Luke, Robson, Craig N.
Publicat 2014

FOXA1 regulates androgen receptor variant activity in models of castrate-resistant prostate cancer

per Jones, Dominic, Wade, Mark, Nakjang, Sirintra, Chaytor, Lewis, Grey, James, Robson, Craig N., Gaughan, Luke
Publicat a Oncotarget (2015)

p68/DdX5 Supports β-Catenin & RNAP II during Androgen Receptor Mediated Transcription in Prostate Cancer

per Clark, Emma L., Hadjimichael, Christiana, Temperley, Richard, Barnard, Amy, Fuller-Pace, Frances V., Robson, Craig N.
Publicat 2013

The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer

per Wade, Mark A., Jones, Dominic, Wilson, Laura, Stockley, Jacqueline, Coffey, Kelly, Robson, Craig N., Gaughan, Luke
Publicat a Nucleic Acids Res (2015)

Human PIRH2 Enhances Androgen Receptor Signaling through Inhibition of Histone Deacetylase 1 and Is Overexpressed in Prostate Cancer

per Logan, Ian R., Gaughan, Luke, McCracken, Stuart R. C., Sapountzi, Vasileia, Leung, Hing Y., Robson, Craig N.
Publicat 2006

Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells

per Munkley, Jennifer, Lafferty, Nicholas P, Kalna, Gabriela, Robson, Craig N, Leung, Hing Y, Rajan, Prabhakar, Elliott, David J
Publicat a BMC Cancer (2015)

The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7

per Stockley, Jacqueline, Markert, Elke, Zhou, Yan, Robson, Craig N., Elliott, David J., Lindberg, Johan, Leung, Hing Y., Rajan, Prabhakar
Publicat a Sci Rep (2015)

The novel anti-androgen candidate galeterone targets deubiquitinating enzymes, USP12 and USP46, to control prostate cancer growth and survival

per McClurg, Urszula L., Azizyan, Mahsa, Dransfield, Daniel T., Namdev, Nivedita, Chit, Nay C.T.H., Nakjang, Sirintra, Robson, Craig N.
Publicat a Oncotarget (2018)

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities

per Kounatidou, Evangelia, Nakjang, Sirintra, McCracken, Stuart R C, Dehm, Scott M, Robson, Craig N, Jones, Dominic, Gaughan, Luke
Publicat a Nucleic Acids Res (2019)

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation

per Munkley, Jennifer, Rajan, Prabhakar, Laferty, Nicholas P., Dalgliesh, Caroline, Jackson, Robert M., Robson, Craig N., Leung, Hing Y., Elliott, David J.
Publicat 2013

Heat shock factor-1 modulates p53 activity in the transcriptional response to DNA damage

per Logan, Ian R., McNeill, Hesta V., Cook, Susan, Lu, Xiaohong, Meek, David W., Fuller-Pace, Frances V., Lunec, John, Robson, Craig N.
Publicat 2009

Deubiquitinating Enzyme Usp12 Is a Novel Co-activator of the Androgen Receptor

per Burska, Urszula L., Harle, Victoria J., Coffey, Kelly, Darby, Steven, Ramsey, Hollie, O'Neill, Daniel, Logan, Ian R., Gaughan, Luke, Robson, Craig N.
Publicat 2013

Nutlin-3 inhibits androgen receptor-driven c-FLIP expression, resulting in apoptosis of prostate cancer cells

per Logan, Ian R., McClurg, Urszula L., Jones, Dominic L., O'Neill, Daniel J., Shaheen, Fadhel S., Lunec, John, Gaughan, Luke, Robson, Craig N.
Publicat a Oncotarget (2016)

Human α(2)β(1) (HI) CD133(+VE) Epithelial Prostate Stem Cells Express Low Levels of Active Androgen Receptor

per Williamson, Stuart C., Hepburn, Anastasia C., Wilson, Laura, Coffey, Kelly, Ryan-Munden, Claudia A., Pal, Deepali, Leung, Hing Y., Robson, Craig N., Heer, Rakesh
Publicat 2012