Are Rodent Models Fit for Investigation of Human Obesity and Related Diseases?

Por Robert K. Semple, Sam Virtue, Gilles Fromentin, Patrick C. Even, Nicholas M. Morton
Publicado no Frontiers Research Topics (2018)

Type B insulin resistance syndrome associated with connective tissue disease and psoriasis

Por Agnieszka Łebkowska, Anna Krentowska, Agnieszka Adamska, Danuta Lipińska, Beata Piasecka, Otylia Kowal-Bielecka, Maria Górska, Robert K Semple, Irina Kowalska
Publicado em 2020-08-01

Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model

Por Jian-Hua Chen, Kim Jee Goh, Nuno Rocha, Matthijs P. Groeneveld, Marina Minic, Timothy G. Barrett, David Savage, Robert K. Semple
Publicado em 2017-12-01

Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure

Por Albert Kwok, Ilona Zvetkova, Sam Virtue, Ineke Luijten, Isabel Huang-Doran, Patsy Tomlinson, David A. Bulger, James West, Steven Murfitt, Julian Griffin, Rafeah Alam, Daniel Hart, Rachel Knox, Peter Voshol, Antonio Vidal-Puig, Jørgen Jensen, Stephen O'Rahilly, Robert K. Semple
Publicado em 2020-10-01

Genome‐Wide Association Study of NAFLD Using Electronic Health Records

Por Cameron J. Fairfield, Thomas M. Drake, Riinu Pius, Andrew D. Bretherick, Archie Campbell, David W. Clark, Jonathan A. Fallowfield, Caroline Hayward, Neil C. Henderson, Peter K. Joshi, Nicholas L. Mills, David J. Porteous, Prakash Ramachandran, Robert K. Semple, Catherine A. Shaw, Cathie L.M. Sudlow, Paul R.H.J. Timmers, James F. Wilson, Stephen J. Wigmore, Ewen M. Harrison, Athina Spiliopoulou
Publicado em 2022-02-01