Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery

由 Powley, Ian R., Patel, Meeta, Miles, Gareth, Pringle, Howard, Howells, Lynne, Thomas, Anne, Kettleborough, Catherine, Bryans, Justin, Hammonds, Tim, MacFarlane, Marion, Pritchard, Catrin
發表在 Br J Cancer (2020)

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

由 Hughes, Michelle A., Powley, Ian R., Jukes-Jones, Rebekah, Horn, Sebastian, Feoktistova, Maria, Fairall, Louise, Schwabe, John W.R., Leverkus, Martin, Cain, Kelvin, MacFarlane, Marion
發表在 Mol Cell (2016)

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

由 Fox, Joanna L., Hughes, Michelle A., Meng, Xin, Sarnowska, Nikola A., Powley, Ian R., Jukes-Jones, Rebekah, Dinsdale, David, Ragan, Timothy J., Fairall, Louise, Schwabe, John W. R., Morone, Nobuhiro, Cain, Kelvin, MacFarlane, Marion
發表在 Nat Commun (2021)

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes

由 Powley, Ian R., Kondrashov, Alexander, Young, Lucy A., Dobbyn, Helen C., Hill, Kirsti, Cannell, Ian G., Stoneley, Mark, Kong, Yi-Wen, Cotes, Julia A., Smith, Graeme C.M., Wek, Ron, Hayes, Christopher, Gant, Timothy W., Spriggs, Keith A., Bushell, Martin, Willis, Anne E.
出版 2009

Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)

由 Chernova, Tatyana, Murphy, Fiona A., Galavotti, Sara, Sun, Xiao-Ming, Powley, Ian R., Grosso, Stefano, Schinwald, Anja, Zacarias-Cabeza, Joaquin, Dudek, Kate M., Dinsdale, David, Le Quesne, John, Bennett, Jonathan, Nakas, Apostolos, Greaves, Peter, Poland, Craig A., Donaldson, Ken, Bushell, Martin, Willis, Anne E., MacFarlane, Marion
發表在 Curr Biol (2017)