Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery

gan Powley, Ian R., Patel, Meeta, Miles, Gareth, Pringle, Howard, Howells, Lynne, Thomas, Anne, Kettleborough, Catherine, Bryans, Justin, Hammonds, Tim, MacFarlane, Marion, Pritchard, Catrin
Cyhoeddwyd yn Br J Cancer (2020)

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

gan Hughes, Michelle A., Powley, Ian R., Jukes-Jones, Rebekah, Horn, Sebastian, Feoktistova, Maria, Fairall, Louise, Schwabe, John W.R., Leverkus, Martin, Cain, Kelvin, MacFarlane, Marion
Cyhoeddwyd yn Mol Cell (2016)

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

gan Fox, Joanna L., Hughes, Michelle A., Meng, Xin, Sarnowska, Nikola A., Powley, Ian R., Jukes-Jones, Rebekah, Dinsdale, David, Ragan, Timothy J., Fairall, Louise, Schwabe, John W. R., Morone, Nobuhiro, Cain, Kelvin, MacFarlane, Marion
Cyhoeddwyd yn Nat Commun (2021)

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes

gan Powley, Ian R., Kondrashov, Alexander, Young, Lucy A., Dobbyn, Helen C., Hill, Kirsti, Cannell, Ian G., Stoneley, Mark, Kong, Yi-Wen, Cotes, Julia A., Smith, Graeme C.M., Wek, Ron, Hayes, Christopher, Gant, Timothy W., Spriggs, Keith A., Bushell, Martin, Willis, Anne E.
Cyhoeddwyd 2009

Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)

gan Chernova, Tatyana, Murphy, Fiona A., Galavotti, Sara, Sun, Xiao-Ming, Powley, Ian R., Grosso, Stefano, Schinwald, Anja, Zacarias-Cabeza, Joaquin, Dudek, Kate M., Dinsdale, David, Le Quesne, John, Bennett, Jonathan, Nakas, Apostolos, Greaves, Peter, Poland, Craig A., Donaldson, Ken, Bushell, Martin, Willis, Anne E., MacFarlane, Marion
Cyhoeddwyd yn Curr Biol (2017)