Modulating ADME Properties by Fluorination: MK2 Inhibitors with Improved Oral Exposure

le Velcicky, Juraj, Schlapbach, Achim, Heng, Richard, Revesz, Laszlo, Pflieger, Daniel, Blum, Ernst, Hawtin, Stuart, Huppertz, Christine, Feifel, Roland, Hersperger, Rene
Foilsithe in ACS Med Chem Lett (2018)

Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors

le Velcicky, Juraj, Mathison, Casey J. N., Nikulin, Victor, Pflieger, Daniel, Epple, Robert, Azimioara, Mihai, Cow, Christopher, Michellys, Pierre-Yves, Rigollier, Pascal, Beisner, Daniel R., Bodendorf, Ursula, Guerini, Danilo, Liu, Bo, Wen, Ben, Zaharevitz, Samantha, Brandl, Trixi
Foilsithe in ACS Med Chem Lett (2019)