Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice

Por Peter H. Schafer, Mary Adams, Gerald Horan, Francesca Truzzi, Alessandra Marconi, Carlo Pincelli
Publicado em 2019-10-01

Spebrutinib (CC-292) Affects Markers of B Cell Activation, Chemotaxis, and Osteoclasts in Patients with Rheumatoid Arthritis: Results from a Mechanistic Study

Por Peter H. Schafer, Alan J. Kivitz, Jianglin Ma, Shimon Korish, Donna Sutherland, Li Li, Ada Azaryan, Jolanta Kosek, Mary Adams, Lori Capone, Eun Mi Hur, Douglas R. Hough, Garth E. Ringheim
Publicado em 2019-11-01

Apremilast Ameliorates Experimental Arthritis via Suppression of Th1 and Th17 Cells and Enhancement of CD4+Foxp3+ Regulatory T Cells Differentiation

Por Weiqian Chen, Weiqian Chen, Julie Wang, Zhenjian Xu, Zhenjian Xu, Feng Huang, Wenbin Qian, Jilin Ma, Hwa bok Wee, Gregory S. Lewis, Rayford R. June, Peter H. Schafer, Jin Lin, Song Guo Zheng
Publicado em 2018-07-01