Series Introduction: The cellular response to aggregated proteins associated with human disease

Yazar: Perlmutter, David H.
Baskı/Yayın Bilgisi 2002

Liver injury in α(1)-antitrypsin deficiency: an aggregated protein induces mitochondrial injury

Yazar: Perlmutter, David H.
Baskı/Yayın Bilgisi 2002

Current and Emerging Treatments for Alpha-1 Antitrypsin Deficiency

Yazar: Perlmutter, David H.
Yayımlandı Gastroenterol Hepatol (N Y) (2016)

α1-antitrypsin Deficiency: A Misfolded Secretory Protein Variant with Unique Effects on the Endoplasmic Reticulum

Yazar: Perlmutter, David H
Yayımlandı Endoplasmic Reticulum Stress Dis (2016)

Washington University: Research, Education, and Innovative Health Care

Yazar: Perlmutter, David H.
Yayımlandı Mo Med (2019)

Novel Treatment Strategies for Liver Disease Due to a1‐Antitrypsin Deficiency

Yazar: Maurice, Nicholas, Perlmutter, David H.
Baskı/Yayın Bilgisi 2012

Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency

Yazar: Wang, Yan, Perlmutter, David H.
Baskı/Yayın Bilgisi 2013

Hepatic Fibrosis and Carcinogenesis in α1-Antitrypsin Deficiency: A Prototype for Chronic Tissue Damage in Gain-of-Function Disorders

Yazar: Perlmutter, David H., Silverman, Gary A.
Baskı/Yayın Bilgisi 2011

Capitalizing on the Autophagic Response for Treatment of Liver Disease Caused by Alpha-1-Antitrypsin Deficiency and Other Genetic Diseases

Yazar: Chu, Andrew S., Perlmutter, David H., Wang, Yan
Baskı/Yayın Bilgisi 2014

Two new considerations for improving the diagnosis of α1-antitrypsin deficiency-associated liver disease

Yazar: Perlmutter, David H, Chopra, Kapil, Chu, Andrew
Yayımlandı Dig Dis Sci (2015)

Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration

Yazar: Rudnick, David A., Perlmutter, David H., Muglia, Louis J.
Baskı/Yayın Bilgisi 2001

Disorders of Protein Misfolding: Alpha-1-antitrypsin Deficiency as Prototype

Yazar: Silverman, Gary A., Pak, Stephen C., Perlmutter, David H.
Baskı/Yayın Bilgisi 2013

Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease

Yazar: Ghouse, Raafe, Chu, Andrew, Wang, Yan, Perlmutter, David H.
Baskı/Yayın Bilgisi 2014

Chemical chaperones mediate increased secretion of mutant α1-antitrypsin (α1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in α1-AT defic...

Yazar: Burrows, Jon A. J., Willis, Lauren K., Perlmutter, David H.
Baskı/Yayın Bilgisi 2000

Clathrin Pit-mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Cancer Cells

Yazar: Gregory, Alyssa D., Hale, Pamela, Perlmutter, David H., Houghton, A. McGarry
Baskı/Yayın Bilgisi 2012

α1-antitrypsin deficiency and the hepatocytes - an elegans solution to drug discovery

Yazar: O’Reilly, Linda P., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Baskı/Yayın Bilgisi 2013

NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

Yazar: Mukherjee, Amitava, Hidvegi, Tunda, Araya, Patrick, Ewing, Michael, Stolz, Donna B., Perlmutter, David H.
Yayımlandı Cell Death Differ (2018)

The Endosomal Protein-Sorting Receptor Sortilin Has a Role in Trafficking α-1 Antitrypsin

Yazar: Gelling, Cristy L., Dawes, Ian W., Perlmutter, David H., Fisher, Edward A., Brodsky, Jeffrey L.
Baskı/Yayın Bilgisi 2012

C. elegans in high-throughput drug discovery

Yazar: O’Reilly, Linda P., Luke, Cliff J., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Baskı/Yayın Bilgisi 2013

Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis

Yazar: Shi, Qingya, Pei, Fen, Silverman, Gary A., Pak, Stephen C., Perlmutter, David H., Liu, Bing, Bahar, Ivet
Yayımlandı Int J Mol Sci (2020)