Series Introduction: The cellular response to aggregated proteins associated with human disease

gan Perlmutter, David H.
Cyhoeddwyd 2002

Liver injury in α(1)-antitrypsin deficiency: an aggregated protein induces mitochondrial injury

gan Perlmutter, David H.
Cyhoeddwyd 2002

Current and Emerging Treatments for Alpha-1 Antitrypsin Deficiency

gan Perlmutter, David H.
Cyhoeddwyd yn Gastroenterol Hepatol (N Y) (2016)

α1-antitrypsin Deficiency: A Misfolded Secretory Protein Variant with Unique Effects on the Endoplasmic Reticulum

gan Perlmutter, David H
Cyhoeddwyd yn Endoplasmic Reticulum Stress Dis (2016)

Washington University: Research, Education, and Innovative Health Care

gan Perlmutter, David H.
Cyhoeddwyd yn Mo Med (2019)

Novel Treatment Strategies for Liver Disease Due to a1‐Antitrypsin Deficiency

gan Maurice, Nicholas, Perlmutter, David H.
Cyhoeddwyd 2012

Targeting intracellular degradation pathways for treatment of liver disease caused by α1-antitrypsin deficiency

gan Wang, Yan, Perlmutter, David H.
Cyhoeddwyd 2013

Hepatic Fibrosis and Carcinogenesis in α1-Antitrypsin Deficiency: A Prototype for Chronic Tissue Damage in Gain-of-Function Disorders

gan Perlmutter, David H., Silverman, Gary A.
Cyhoeddwyd 2011

Capitalizing on the Autophagic Response for Treatment of Liver Disease Caused by Alpha-1-Antitrypsin Deficiency and Other Genetic Diseases

gan Chu, Andrew S., Perlmutter, David H., Wang, Yan
Cyhoeddwyd 2014

Two new considerations for improving the diagnosis of α1-antitrypsin deficiency-associated liver disease

gan Perlmutter, David H, Chopra, Kapil, Chu, Andrew
Cyhoeddwyd yn Dig Dis Sci (2015)

Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration

gan Rudnick, David A., Perlmutter, David H., Muglia, Louis J.
Cyhoeddwyd 2001

Disorders of Protein Misfolding: Alpha-1-antitrypsin Deficiency as Prototype

gan Silverman, Gary A., Pak, Stephen C., Perlmutter, David H.
Cyhoeddwyd 2013

Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease

gan Ghouse, Raafe, Chu, Andrew, Wang, Yan, Perlmutter, David H.
Cyhoeddwyd 2014

Chemical chaperones mediate increased secretion of mutant α1-antitrypsin (α1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in α1-AT defic...

gan Burrows, Jon A. J., Willis, Lauren K., Perlmutter, David H.
Cyhoeddwyd 2000

Clathrin Pit-mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Cancer Cells

gan Gregory, Alyssa D., Hale, Pamela, Perlmutter, David H., Houghton, A. McGarry
Cyhoeddwyd 2012

α1-antitrypsin deficiency and the hepatocytes - an elegans solution to drug discovery

gan O’Reilly, Linda P., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Cyhoeddwyd 2013

NFκB mitigates the pathological effects of misfolded α1-antitrypsin by activating autophagy and an integrated program of proteostasis mechanisms

gan Mukherjee, Amitava, Hidvegi, Tunda, Araya, Patrick, Ewing, Michael, Stolz, Donna B., Perlmutter, David H.
Cyhoeddwyd yn Cell Death Differ (2018)

The Endosomal Protein-Sorting Receptor Sortilin Has a Role in Trafficking α-1 Antitrypsin

gan Gelling, Cristy L., Dawes, Ian W., Perlmutter, David H., Fisher, Edward A., Brodsky, Jeffrey L.
Cyhoeddwyd 2012

C. elegans in high-throughput drug discovery

gan O’Reilly, Linda P., Luke, Cliff J., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Cyhoeddwyd 2013

Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis

gan Shi, Qingya, Pei, Fen, Silverman, Gary A., Pak, Stephen C., Perlmutter, David H., Liu, Bing, Bahar, Ivet
Cyhoeddwyd yn Int J Mol Sci (2020)