Using recombination-dependent lethal mutations to stabilize reporter flaviviruses for rapid serodiagnosis and drug discovery

Por Coleman Baker, Xuping Xie, Jing Zou, Antonio Muruato, Katja Fink, Pei-Yong Shi
Publicado em 2020-07-01

Crystal structure of the dengue virus methyltransferase bound to a 5'-capped octameric RNA.

Por Li Jian Yap, Dahai Luo, Ka Yan Chung, Siew Pheng Lim, Christophe Bodenreider, Christian Noble, Pei-Yong Shi, Julien Lescar
Publicado em 2010-09-01

A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients

Por Chao Shan, Xuping Xie, Ping Ren, Michael J. Loeffelholz, Yujiao Yang, Andrea Furuya, Alan P. Dupuis, II, Laura D. Kramer, Susan J. Wong, Pei-Yong Shi
Publicado em 2017-03-01

Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant

Por Yang Liu, Jianying Liu, Bryan A. Johnson, Hongjie Xia, Zhiqiang Ku, Craig Schindewolf, Steven G. Widen, Zhiqiang An, Scott C. Weaver, Vineet D. Menachery, Xuping Xie, Pei-Yong Shi
Publicado em 2022-05-01

A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication.

Por Yongqian Zhao, Tingjin Sherryl Soh, Jie Zheng, Kitti Wing Ki Chan, Wint Wint Phoo, Chin Chin Lee, Moon Y F Tay, Kunchithapadam Swaminathan, Tobias C Cornvik, Siew Pheng Lim, Pei-Yong Shi, Julien Lescar, Subhash G Vasudevan, Dahai Luo
Publicado em 2015-03-01

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.

Por Siew Pheng Lim, Christian Guy Noble, Cheah Chen Seh, Tingjin Sherryl Soh, Abbas El Sahili, Grace Kar Yarn Chan, Julien Lescar, Rishi Arora, Timothy Benson, Shahul Nilar, Ujjini Manjunatha, Kah Fei Wan, Hongping Dong, Xuping Xie, Pei-Yong Shi, Fumiaki Yokokawa
Publicado em 2016-08-01

Mouse-adapted SARS-CoV-2 protects animals from lethal SARS-CoV challenge.

Por Antonio Muruato, Michelle N Vu, Bryan A Johnson, Meredith E Davis-Gardner, Abigail Vanderheiden, Kumari Lokugamage, Craig Schindewolf, Patricia A Crocquet-Valdes, Rose M Langsjoen, Jessica A Plante, Kenneth S Plante, Scott C Weaver, Kari Debbink, Andrew L Routh, David Walker, Mehul S Suthar, Pei-Yong Shi, Xuping Xie, Vineet D Menachery
Publicado em 2021-11-01

Characterization of a 2016 Clinical Isolate of Zika Virus in Non-human Primates

Por Xiao-Feng Li, Hao-Long Dong, Xing-Yao Huang, Ye-Feng Qiu, Hong-Jiang Wang, Yong-Qiang Deng, Na-Na Zhang, Qing Ye, Hui Zhao, Zhong-Yu Liu, Hang Fan, Xiao-Ping An, Shi-Hui Sun, Bo Gao, Yun-Zhi Fa, Yi-Gang Tong, Fu-Chun Zhang, George F. Gao, Wu-Chun Cao, Pei-Yong Shi, Cheng-Feng Qin
Publicado em 2016-10-01

Zika Virus Epidemic in Brazil. II. Post-Mortem Analyses of Neonates with Microcephaly, Stillbirths, and Miscarriage

Por Raimunda S. S. Azevedo, Marialva T. Araujo, Consuelo S. Oliveira, Arnaldo Jorge Martins Filho, Bruno T. D. Nunes, Daniele F. Henriques, Eliana V. P. Silva, Valéria L. Carvalho, Jannifer O. Chiang, Lívia C. Martins, Barbara C. B. Vasconcelos, Jorge R. Sousa, Fernanda Montenegro C. Araujo, Erlane M. Ribeiro, Andrezza R. P. Castro, Maria G. L. de Queiroz, Mariana P. Verotti, Márcio R. T. Nunes, Ana C. R. Cruz, Sueli G. Rodrigues, Pei-Yong Shi, Juarez A. S. Quaresma, Robert B. Tesh, Pedro F. C. Vasconcelos
Publicado em 2018-11-01