Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the β2-adrenergic receptor

por Nabhan, Joseph F, Pan, Hui, Lu, Quan
Publicado 2010

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

por Nabhan, Joseph F., Hu, Ruoxi, Oh, Raymond S., Cohen, Stanley N., Lu, Quan
Publicado 2012

Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi

por Moreno, Yovany, Nabhan, Joseph F., Solomon, Jonathan, Mackenzie, Charles D., Geary, Timothy G.
Publicado 2010

Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin

por Nabhan, Joseph F., Gooch, Renea L., Piatnitski Chekler, Eugene L., Pierce, Betsy, Bulawa, Christine E.
Publicado en Sci Rep (2015)

A novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulation

por Jiang, Xiaofeng, Pan, Hui, Nabhan, Joseph F., Krishnan, Ramaswamy, Koziol-White, Cynthia, Panettieri, Reynold A., Lu, Quan
Publicado 2012

Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity

por Fox, Nicholas G., Martelli, Alain, Nabhan, Joseph F., Janz, Jay, Borkowska, Oktawia, Bulawa, Christine, Yue, Wyatt W.
Publicado en Biochimie (2018)

4′-Phosphopantetheine and long acyl chain-dependent interactions are integral to human mitochondrial acyl carrier protein function

por Majmudar, Jaimeen D., Feng, Xidong, Fox, Nicholas G., Nabhan, Joseph F., Towle, Theresa, Ma, Tiffany, Gooch, Renea, Bulawa, Christine, Yue, Wyatt W., Martelli, Alain
Publicado en Medchemcomm (2019)

Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism

por Fox, Nicholas G., Yu, Xiaodi, Feng, Xidong, Bailey, Henry J., Martelli, Alain, Nabhan, Joseph F., Strain-Damerell, Claire, Bulawa, Christine, Yue, Wyatt W., Han, Seungil
Publicado en Nat Commun (2019)

Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich’s ataxia

por Nabhan, Joseph F., Wood, Kristy M., Rao, Varada P., Morin, Jeffrey, Bhamidipaty, Surya, LaBranche, Timothy P., Gooch, Renea L., Bozal, Fazli, Bulawa, Christine E., Guild, Braydon C.
Publicado en Sci Rep (2016)

Correlation between frataxin expression and contractility revealed by in vitro Friedreich’s ataxia cardiac tissue models engineered from human pluripotent stem cells

por Wong, Andy On-Tik, Wong, Gabriel, Shen, Michael, Chow, Maggie Zi-Ying, Tse, Wan Wai, Gurung, Bimal, Mak, Suet Yee, Lieu, Deborah K., Costa, Kevin D., Chan, Camie W., Martelli, Alain, Nabhan, Joseph F., Li, Ronald A.
Publicado en Stem Cell Res Ther (2019)