Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model

por Moore, Kate M., Cerqueira, Vera, MacLeod, Kenneth G., Mullen, Peter, Hayward, Richard L., Green, Simon, Harrison, David J., Cameron, David A., Langdon, Simon P.
Publicado no Explor Target Antitumor Ther (2022)

Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus

por Moore, Kate M., Desai, Ami, Delgado, Bea de Luxán, Trabulo, Sara Maria David, Reader, Claire, Brown, Nicholas F., Murray, Elizabeth R., Brentnall, Adam, Howard, Philip, Masterson, Luke, Zammarchi, Francesca, Hartley, John A., van Berkel, Patrick H., Marshall, John F.
Publicado no Theranostics (2020)

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer

por Fearon, Abbie E., Carter, Edward P., Clayton, Natasha S., Wilkes, Edmund H., Baker, Ann-Marie, Kapitonova, Ekaterina, Bakhouche, Bakhouche A., Tanner, Yasmine, Wang, Jun, Gadaleta, Emanuela, Chelala, Claude, Moore, Kate M., Marshall, John F., Chupin, Juliette, Schmid, Peter, Jones, J. Louise, Lockley, Michelle, Cutillas, Pedro R., Grose, Richard P.
Publicado no Cell Rep (2018)

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

por Reader, Claire S, Vallath, Sabari, Steele, Colin W, Haider, Syed, Brentnall, Adam, Desai, Ami, Moore, Kate M, Jamieson, Nigel B, Chang, David, Bailey, Peter, Scarpa, Aldo, Lawlor, Rita, Chelala, Claude, Keyse, Stephen M, Biankin, Andrew, Morton, Jennifer P, Evans, TR Jeffry, Barry, Simon T, Sansom, Owen J, Kocher, Hemant M, Marshall, John F
Publicado no J Pathol (2019)

Therapeutic Targeting of Integrin αvβ6 in Breast Cancer

por Moore, Kate M., Thomas, Gareth J., Duffy, Stephen W., Warwick, Jane, Gabe, Rhian, Chou, Patrick, Ellis, Ian O., Green, Andrew R., Haider, Syed, Brouilette, Kellie, Saha, Antonio, Vallath, Sabari, Bowen, Rebecca, Chelala, Claude, Eccles, Diana, Tapper, William J., Thompson, Alastair M., Quinlan, Phillip, Jordan, Lee, Gillett, Cheryl, Brentnall, Adam, Violette, Shelia, Weinreb, Paul H., Kendrew, Jane, Barry, Simon T., Hart, Ian R., Jones, J. Louise, Marshall, John F.
Publicado em 2014