Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model

by Moore, Kate M., Cerqueira, Vera, MacLeod, Kenneth G., Mullen, Peter, Hayward, Richard L., Green, Simon, Harrison, David J., Cameron, David A., Langdon, Simon P.
Published in Explor Target Antitumor Ther (2022)

Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus

by Moore, Kate M., Desai, Ami, Delgado, Bea de Luxán, Trabulo, Sara Maria David, Reader, Claire, Brown, Nicholas F., Murray, Elizabeth R., Brentnall, Adam, Howard, Philip, Masterson, Luke, Zammarchi, Francesca, Hartley, John A., van Berkel, Patrick H., Marshall, John F.
Published in Theranostics (2020)

PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer

by Fearon, Abbie E., Carter, Edward P., Clayton, Natasha S., Wilkes, Edmund H., Baker, Ann-Marie, Kapitonova, Ekaterina, Bakhouche, Bakhouche A., Tanner, Yasmine, Wang, Jun, Gadaleta, Emanuela, Chelala, Claude, Moore, Kate M., Marshall, John F., Chupin, Juliette, Schmid, Peter, Jones, J. Louise, Lockley, Michelle, Cutillas, Pedro R., Grose, Richard P.
Published in Cell Rep (2018)

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

by Reader, Claire S, Vallath, Sabari, Steele, Colin W, Haider, Syed, Brentnall, Adam, Desai, Ami, Moore, Kate M, Jamieson, Nigel B, Chang, David, Bailey, Peter, Scarpa, Aldo, Lawlor, Rita, Chelala, Claude, Keyse, Stephen M, Biankin, Andrew, Morton, Jennifer P, Evans, TR Jeffry, Barry, Simon T, Sansom, Owen J, Kocher, Hemant M, Marshall, John F
Published in J Pathol (2019)

Therapeutic Targeting of Integrin αvβ6 in Breast Cancer

by Moore, Kate M., Thomas, Gareth J., Duffy, Stephen W., Warwick, Jane, Gabe, Rhian, Chou, Patrick, Ellis, Ian O., Green, Andrew R., Haider, Syed, Brouilette, Kellie, Saha, Antonio, Vallath, Sabari, Bowen, Rebecca, Chelala, Claude, Eccles, Diana, Tapper, William J., Thompson, Alastair M., Quinlan, Phillip, Jordan, Lee, Gillett, Cheryl, Brentnall, Adam, Violette, Shelia, Weinreb, Paul H., Kendrew, Jane, Barry, Simon T., Hart, Ian R., Jones, J. Louise, Marshall, John F.
Published 2014