Alkylsulfone-containing trisubstituted cyclohexanes as potent and bioavailable chemokine receptor 2 (CCR2) antagonists

Por Cherney, Robert J., Mo, Ruowei, Yang, Michael G., Xiao, Zili, Zhao, Qihong, Mandlekar, Sandhya, Cvijic, Mary Ellen, Charo, Israel F., Barrish, Joel C., Decicco, Carl P., Carter, Percy H.
Publicado no Bioorg Med Chem Lett (2014)

Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5

Por Carter, Percy H., Brown, Gregory D., Cherney, Robert J., Batt, Douglas G., Chen, Jing, Clark, Cheryl M., Cvijic, Mary Ellen, Duncia, John V., Ko, Soo S., Mandlekar, Sandhya, Mo, Ruowei, Nelson, David J., Pang, Jian, Rose, Anne V., Santella, Joseph B., Tebben, Andrew J., Traeger, Sarah C., Xu, Songmei, Zhao, Qihong, Barrish, Joel C.
Publicado no ACS Med Chem Lett (2015)