Use of in-silico assays to characterize the ADMET profile and identify potential therapeutic targets of fusarochromanone, a novel anti-cancer agent

Por El-Saadi, Madison Wynne, Williams-Hart, Tara, Salvatore, Brian A, Mahdavian, Elahe
Publicado no In Silico Pharmacol (2015)

Caspase-dependent signaling underlies glioblastoma cell death in response to the fungal metabolite, fusarochromanone

Por MAHDAVIAN, ELAHE, MARSHALL, MONIQUE, MARTIN, PATRICK M., CAGLE, PATRICE, SALVATORE, BRIAN A., QUICK, QUINCY A.
Publicado em 2014

Fusarochromanone Induces G(1) Cell Cycle Arrest and Apoptosis in COS7 and HEK293 Cells

Por Gu, Ying, Chen, Xin, Shang, Chaowei, Singh, Karnika, Barzegar, Mansoureh, Mahdavian, Elahe, Salvatore, Brian A., Jiang, Shanxiang, Huang, Shile
Publicado no PLoS One (2014)

Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5

Por Gu, Ying, Barzegar, Mansoureh, Chen, Xin, Wu, Yang, Shang, Chaowei, Mahdavian, Elahe, Salvatore, Brian A., Jiang, Shanxiang, Huang, Shile
Publicado no Oncotarget (2015)

Biological activities of fusarochromanone: a potent anti-cancer agent

Por Mahdavian, Elahe, Palyok, Phillip, Adelmund, Steven, Williams-Hart, Tara, Furmanski, Brian D, Kim, Yoon-Jee, Gu, Ying, Barzegar, Mansoureh, Wu, Yang, Bhinge, Kaustubh N, Kolluru, Gopi K, Quick, Quincy, Liu, Yong-Yu, Kevil, Christopher G, Salvatore, Brian A, Huang, Shile, Clifford, John L
Publicado em 2014

Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II

Por Dong, Lan-Feng, Jameson, Victoria J. A., Tilly, David, Cerny, Jiri, Mahdavian, Elahe, Marín-Hernández, Alvaro, Hernández-Esquivel, Luz, Rodríguez-Enríquez, Sara, Stursa, Jan, Witting, Paul K., Stantic, Bela, Rohlena, Jakub, Truksa, Jaroslav, Kluckova, Katarina, Dyason, Jeffrey C., Ledvina, Miroslav, Salvatore, Brian A., Moreno-Sánchez, Rafael, Coster, Mark J., Ralph, Stephen J., Smith, Robin A. J., Neuzil, Jiri
Publicado em 2011