Structural Modification of Pantothenamides Counteracts Degradation by Pantetheinase and Improves Antiplasmodial Activity

Por de Villiers, Marianne, Macuamule, Cristiano, Spry, Christina, Hyun, Yoo-Min, Strauss, Erick, Saliba, Kevin J.
Publicado em 2013

Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated

Por Spry, Christina, Macuamule, Cristiano, Lin, Zhiyang, Virga, Kristopher G., Lee, Richard E., Strauss, Erick, Saliba, Kevin J.
Publicado em 2013

A Pantetheinase-Resistant Pantothenamide with Potent, On-Target, and Selective Antiplasmodial Activity

Por Macuamule, Cristiano J., Tjhin, Erick T., Jana, Collins E., Barnard, Leanne, Koekemoer, Lizbé, de Villiers, Marianne, Saliba, Kevin J., Strauss, Erick
Publicado no Antimicrob Agents Chemother (2015)