An analysis of retinal gene therapy clinical trials: successful translation will depend on successful translation

Por MacLaren, Robert E
Publicado em 2009

Comment: Gene Therapy for Age-related Macular Degeneration

Por MacLaren, Robert E
Publicado no Lancet (2015)

Cone fusion confusion in photoreceptor transplantation

Por MacLaren, Robert E.
Publicado no Stem Cell Investig (2017)

Stem cells as a therapeutic tool for the blind: biology and future prospects

Por Singh, Mandeep S., MacLaren, Robert E.
Publicado em 2011

Recent advances and future prospects in choroideremia

Por Zinkernagel, Martin S, MacLaren, Robert E
Publicado no Clin Ophthalmol (2015)

Ocular gene therapy for choroideremia: clinical trials and future perspectives

Por Xue, Kanmin, MacLaren, Robert E.
Publicado no Expert Rev Ophthalmol (2018)

Correcting visual loss by genetics and prosthetics

Por Xue, Kanmin, MacLaren, Robert E.
Publicado no Curr Opin Physiol (2020)

Translating Induced Pluripotent Stem Cells from Bench to Bedside: Application to Retinal Diseases

Por Cramer, Alona O., MacLaren, Robert E.
Publicado em 2013


The Application of CRISPR/Cas9 for the Treatment of Retinal Diseases


Por Peddle, Caroline F., MacLaren, Robert E.
Publicado no Yale J Biol Med (2017)

Comment on: ‘Sector retinitis pigmentosa caused by mutations of the RHO gene’

Por Orlans, Harry O., MacLaren, Robert E.
Publicado no Eye (Lond) (2019)

Induced pluripotent stem cell therapies for retinal disease

Por Comyn, Oliver, Lee, Edward, MacLaren, Robert E
Publicado em 2010

Gene therapy for retinal disease

Por McClements, Michelle E, MacLaren, Robert E
Publicado em 2013


Adeno-associated Virus (AAV) Dual Vector Strategies for Gene Therapy Encoding Large Transgenes

Por McClements, Michelle E., MacLaren, Robert E.
Publicado no Yale J Biol Med (2017)

Novel non-sense mutation in RP2 (c.843_844insT/p.Arg282fs) is associated with a severe phenotype of retinitis pigmentosa without evidence of primary retinal pigment epithelium invo...

Por Horner, Faye, Wawrzynski, James, MacLaren, Robert E
Publicado no BMJ Case Rep (2019)

Gene Therapy for Choroideremia Using an Adeno-Associated Viral (AAV) Vector

Por Barnard, Alun R., Groppe, Markus, MacLaren, Robert E.
Publicado no Cold Spring Harb Perspect Med (2015)

Selective Automated Perimetry Under Photopic, Mesopic, and Scotopic Conditions: Detection Mechanisms and Testing Strategies

Por Simunovic, Matthew P., Moore, Anthony T., MacLaren, Robert E.
Publicado no Transl Vis Sci Technol (2016)

Gene Therapy and Stem Cell Transplantation in Retinal Disease: The New Frontier

Por MacLaren, Robert E., Bennett, Jean, Schwartz, Steven D.
Publicado no Ophthalmology (2016)

Outcome Measures Used in Ocular Gene Therapy Trials: A Scoping Review of Current Practice

Por Jolly, Jasleen K., Bridge, Holly, MacLaren, Robert E.
Publicado no Front Pharmacol (2019)

Monitoring progression of retinitis pigmentosa: current recommendations and recent advances

Por Menghini, Moreno, Cehajic-Kapetanovic, Jasmina, MacLaren, Robert E
Publicado no Expert Opin Orphan Drugs (2020)

Risks of gene therapy should be weighed against lack of alternatives for many diseases

Por MacLaren, Robert E, Ali, Robin R, Thrasher, Adrian J
Publicado em 2005