Discovery, Development, and Adoption of Medications to Treat Alcohol Use Disorder: Goals for the Phases of Medications Development

Por Litten, Raye Z., Falk, Daniel E., Ryan, Megan L., Fertig, Joanne B.
Publicado no Alcohol Clin Exp Res (2016)

Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders

Por Kwako, Laura E., Momenan, Reza, Litten, Raye Z., Koob, George F., Goldman, David
Publicado no Biol Psychiatry (2015)

Moderators of Varenicline Treatment Effects in a Double-Blind, Placebo-Controlled Trial for Alcohol Dependence: an Exploratory Analysis

Por Falk, Daniel E., Castle, I-Jen P., Ryan, Megan, Fertig, Joanne, Litten, Raye Z.
Publicado no J Addict Med (2015)

Cumulative Proportion of Responders Analysis (CPRA) as a Tool to Assess Treatment Outcome in Alcohol Clinical Trials

Por Falk, Daniel E, Litten, Raye Z, Anton, Raymond F, Kranzler, Henry R, Johnson, Bankole A
Publicado em 2014

An Exploratory Evaluation of Take Control: a Novel Computer-Delivered Behavioral Platform for Placebo-Controlled Pharmacotherapy Trials for Alcohol Use Disorder

Por Devine, Eric G, Ryan, Megan L, Falk, Daniel E, Fertig, Joanne B, Litten, Raye Z
Publicado no Contemp Clin Trials (2016)

Five-Year Health Care Utilization and Costs among Lower-Risk Drinkers following Alcohol Treatment

Por Kline-Simon, Andrea H., Weisner, Constance M., Parthasarthy, Sujaya, Falk, Daniel E., Litten, Raye Z., Mertens, Jennifer R.
Publicado em 2013

The Placebo Effect in Clinical Trials for Alcohol Dependence: An Exploratory Analysis of 51 Naltrexone and Acamprosate Studies

Por Litten, Raye Z., Castle, I-Jen P., Falk, Daniel, Ryan, Megan, Fertig, Joanne, Chen, Chiung M., Yi, Hsiao-ye
Publicado em 2013

Posttreatment Low-Risk Drinking as a Predictor of Future Drinking and Problem Outcomes Among Individuals with Alcohol Use Disorders

Por Kline-Simon, Andrea H., Falk, Daniel E., Litten, Raye Z., Mertens, Jennifer R., Fertig, Joanne, Ryan, Megan, Weisner, Constance M.
Publicado em 2012

Methods to Analyze Treatment Effects in the Presence of Missing Data for a Continuous Heavy Drinking Outcome Measure when Participants Drop Out from Treatment in Alcohol Clinical T...

Por Witkiewitz, Katie, Falk, Daniel E., Kranzler, Henry R., Litten, Raye Z., Hallgren, Kevin A., O'Malley, Stephanie S., Anton, Raymond F.
Publicado no Alcohol Clin Exp Res (2014)

Medications Development to Treat Alcohol Dependence: A Vision for the Next Decade

Por Litten, Raye Z., Egli, Mark, Heilig, Markus, Cui, Changhai, Fertig, Joanne B., Ryan, Megan L., Falk, Daniel E., Moss, Howard, Huebner, Robert, Noronha, Antonio
Publicado em 2012

Risks of Alcohol Use Disorders Related to Drinking Patterns in the U.S. General Population

Por Greenfield, Thomas K, Ye, Yu, Bond, Jason, Kerr, William C, Nayak, Madhabika B, Kaskutas, Lee Ann, Anton, Raymond F, Litten, Raye Z, Kranzler, Henry R
Publicado em 2014

Clinical Validation of Reduced Alcohol Consumption After Treatment for Alcohol Dependence Using the World Health Organization Risk Drinking Levels

Por Witkiewitz, Katie, Hallgren, Kevin A., Kranzler, Henry R., Mann, Karl F., Hasin, Deborah S., Falk, Daniel E., Litten, Raye Z., O'Malley, Stephanie S., Anton, Raymond F.
Publicado no Alcohol Clin Exp Res (2016)

The Alcohol Clinical Trials Initiative (ACTIVE): Purpose and Goals for Assessing Important and Salient Issues for Medications Development in Alcohol Use Disorders

Por Anton, Raymond F, Litten, Raye Z, Falk, Daniel E, Palumbo, Joseph M, Bartus, Raymond T, Robinson, Rebecca L, Kranzler, Henry R, Kosten, Thomas R, Meyer, Roger E, O'Brien, Charles P, Mann, Karl, Meulien, Didier
Publicado em 2012

A Double-Blind, Placebo-Controlled Trial to Assess the Efficacy of Quetiapine Fumarate in Very Heavy Drinking Alcohol-Dependent Patients

Por Litten, Raye Z., Fertig, Joanne B., Falk, Daniel E., Ryan, Megan L., Mattson, Margaret E., Collins, Joseph F., Murtaugh, Cristin, Ciraulo, Domenic, Green, Alan I., Johnson, Bankole, Pettinati, Helen, Swift, Robert, Afshar, Maryam, Brunette, Mary F., Tiouririne, Nassima Ait-Daoud, Kampman, Kyle, Stout, Robert
Publicado em 2011

A Double-Blind, Placebo-Controlled Trial Assessing the Efficacy of Varenicline Tartrate for Alcohol Dependence

Por Litten, Raye Z., Ryan, Megan L., Fertig, Joanne B., Falk, Daniel E., Johnson, Bankole, Dunn, Kelly E., Green, Alan I., Pettinati, Helen M., Ciraulo, Domenic A., Sarid-Segal, Ofra, Kampman, Kyle, Brunette, Mary F., Strain, Eric C., Tiouririne, Nassima A., Ransom, Janet, Scott, Charles, Stout, Robert
Publicado em 2013

A Double-Blind, Placebo-Controlled Trial Assessing the Efficacy of Levetiracetam Extended Release in Very Heavy Drinking Alcohol-Dependent Patients

Por Fertig, Joanne B., Ryan, Megan L., Falk, Daniel E., Litten, Raye Z., Mattson, Margaret E., Ransom, Janet, Rickman, William J., Scott, Charles, Ciraulo, Domenic, Green, Alan I., Tiouririne, Nassima Ait-Daoud, Johnson, Bankole, Pettinati, Helen, Strain, Eric C., Devine, Eric, Brunette, Mary F., Kampman, Kyle, Tompkins, D. Andrew, Stout, Robert
Publicado em 2012

Measures of Outcome for Stimulant Trials: ACTTION Recommendations and Research Agenda

Por Kiluk, Brian D., Carroll, Kathleen M., Duhig, Amy, Falk, Daniel E., Kampman, Kyle, Lai, Shengan, Litten, Raye Z., McCann, David J., Montoya, Ivan D., Preston, Kenzie L., Skolnick, Phil, Weisner, Constance, Woody, George, Chandler, Redonna, Detke, Michael J., Dunn, Kelly, Dworkin, Robert H., Fertig, Joanne, Gewandter, Jennifer, Moeller, F. Gerard, Ramey, Tatiana, Ryan, Megan, Silverman, Kenneth, Strain, Eric C.
Publicado no Drug Alcohol Depend (2015)