An update of clinical issues from InSIGHT 2011

Por Lipton, L
Publicado em 2012

Cognition-activated low-frequency modulation of light absorption in human brain.

Por Chance, B, Zhuang, Z, UnAh, C, Alter, C, Lipton, L
Publicado em 1993

Germline mutations in the TGF-ß and Wnt signalling pathways are a rare cause of the "multiple" adenoma phenotype

Por Lipton, L, Sieber, O, Thomas, H, Hodgson, S, Tomlinson, I, Woodford-Richens, K
Publicado em 2003

Safety and pharmacokinetics of motesanib in combination with gemcitabine for the treatment of patients with solid tumours

Por Price, T J, Lipton, L, McGreivy, J, McCoy, S, Sun, Y-N, Rosenthal, M A
Publicado em 2008

Analysis of somatic molecular changes, clinicopathological features, family history, and germline mutations in colorectal cancer families: evidence for efficient diagnosis of HNPCC...

Por Johnson, V, Lipton, L, Cummings, C, Eftekhar, S, Izatt, L, Hodgson, S, Talbot, I, Thomas, H, Silver, A, Tomlinson, I
Publicado em 2005

Audit of routine immunohistochemistry testing for mismatch repair proteins at diagnosis of colorectal cancer under the age of 50

Por Lipton, L, Kentwell, M, Li, M, Williams, D, Christie, M, Landgren, A, Dow, C, Jones, I, McLaughlin, S, Delatycki, M, Macrae, F, Lynch, E
Publicado em 2012

The TERT variant rs2736100 is associated with colorectal cancer risk

Por Kinnersley, B, Migliorini, G, Broderick, P, Whiffin, N, Dobbins, S E, Casey, G, Hopper, J, Sieber, O, Lipton, L, Kerr, D J, Dunlop, M G, Tomlinson, I PM, Houlston, R S
Publicado em 2012

A phase 3 randomized, double-blind, placebo-controlled trial of ganitumab or placebo in combination with gemcitabine as first-line therapy for metastatic adenocarcinoma of the panc...

Por Fuchs, C. S., Azevedo, S., Okusaka, T., Van Laethem, J.-L., Lipton, L. R., Riess, H., Szczylik, C., Moore, M. J., Peeters, M., Bodoky, G., Ikeda, M., Melichar, B., Nemecek, R., Ohkawa, S., Świeboda-Sadlej, A., Tjulandin, S. A., Van Cutsem, E., Loberg, R., Haddad, V., Gansert, J. L., Bach, B. A., Carrato, A.
Publicado no Ann Oncol (2015)

Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or “multiple” colorectal adenomas

Por Sieber, O. M., Lamlum, H., Crabtree, M. D., Rowan, A. J., Barclay, E., Lipton, L., Hodgson, S., Thomas, H. J. W., Neale, K., Phillips, R. K. S., Farrington, S. M., Dunlop, M. G., Mueller, H. J., Bisgaard, M. L., Bulow, S., Fidalgo, P., Albuquerque, C., Scarano, M. I., Bodmer, W., Tomlinson, I. P. M., Heinimann, K.
Publicado em 2002

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis

Por Christie, M, Jorissen, R N, Mouradov, D, Sakthianandeswaren, A, Li, S, Day, F, Tsui, C, Lipton, L, Desai, J, Jones, I T, McLaughlin, S, Ward, R L, Hawkins, N J, Ruszkiewicz, A R, Moore, J, Burgess, A W, Busam, D, Zhao, Q, Strausberg, R L, Simpson, A J, Tomlinson, I P M, Gibbs, P, Sieber, O M
Publicado em 2013

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

Por Win, A K, Dowty, J G, English, D R, Campbell, P T, Young, J P, Winship, I, Macrae, F A, Lipton, L, Parry, S, Young, G P, Buchanan, D D, Martínez, M E, Jacobs, E T, Ahnen, D J, Haile, R W, Casey, G, Baron, J A, Lindor, N M, Thibodeau, S N, Newcomb, P A, Potter, J D, Le Marchand, L, Gallinger, S, Hopper, J L, Jenkins, M A
Publicado em 2011

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

Por Tomlinson, I P M, Dunlop, M, Campbell, H, Zanke, B, Gallinger, S, Hudson, T, Koessler, T, Pharoah, P D, Niittymäkix, I, Tuupanenx, S, Aaltonen, L A, Hemminki, K, Lindblom, A, Försti, A, Sieber, O, Lipton, L, van Wezel, T, Morreau, H, Wijnen, J T, Devilee, P, Matsuda, K, Nakamura, Y, Castellví-Bel, S, Ruiz-Ponte, C, Castells, A, Carracedo, A, Ho, J W C, Sham, P, Hofstra, R M W, Vodicka, P, Brenner, H, Hampe, J, Schafmayer, C, Tepel, J, Schreiber, S, Völzke, H, Lerch, M M, Schmidt, C A, Buch, S, Moreno, V, Villanueva, C M, Peterlongo, P, Radice, P, Echeverry, M M, Velez, A, Carvajal-Carmona, L, Scott, R, Penegar, S, Broderick, P, Tenesa, A, Houlston, R S
Publicado em 2010

COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer

Por Tomlinson, I P M, Dunlop, M, Campbell, H, Zanke, B, Gallinger, S, Hudson, T, Koessler, T, Pharoah, P D, Niittymäki, I, Tuupanen, S, Aaltonen, L A, Hemminki, K, Lindblom, A, Försti, A, Sieber, O, Lipton, L, van Wezel, T, Morreau, H, Wijnen, J T, Devilee, P, Matsuda, K, Nakamura, Y, Castellví-Bel, S, Ruiz-Ponte, C, Castells, A, Carracedo, A, Ho, J W C, Sham, P, Hofstra, R M W, Vodicka, P, Brenner, H, Hampe, J, Schafmayer, C, Tepel, J, Schreiber, S, Völzke, H, Lerch, M M, Schmidt, C A, Buch, S, Moreno, V, Villanueva, C M, Peterlongo, P, Radice, P, Echeverry, M M, Velez, A, Carvajal-Carmona, L, Scott, R, Penegar, S, Broderick, P, Tenesa, A, Houlston, R S
Publicado em 2010