Toward the Scale-Up of a Bicyclic Homopiperazine via Schmidt Rearrangement and Photochemical Oxaziridine Rearrangement in Continuous-Flow

door Brown, Michael, Aljarah, Mohammed, Asiki, Hannah, Leung, Leo M. H., Smithen, Deborah A., Miller, Natalie, Nemeth, Gabor, Davies, Lawrence, Niculescu-Duvaz, Dan, Zambon, Alfonso, Springer, Caroline
Gepubliceerd in Org Process Res Dev (2020)

2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth

door Smithen, Deborah A., Leung, Leo M. H., Challinor, Mairi, Lawrence, Rae, Tang, HaoRan, Niculescu-Duvaz, Dan, Pearce, Simon P., Mcleary, Robert, Lopes, Filipa, Aljarah, Mohammed, Brown, Michael, Johnson, Louise, Thomson, Graeme, Marais, Richard, Springer, Caroline
Gepubliceerd in J Med Chem (2019)