Transforming epitope-specific gp120 monomer-based probes into immunogens with N-linked glycan masking

Por Chuang, G, Boyington, JC, Nabel, GJ, Kwong, PD, Georgiev, I
Publicado em 2012

P09-05. Mechanism of HIV-1 resistance to a monoclonal antibody that effectively targets the site of CD4 attachment

Por Wu, X, Zhou, T, O'Dell, S, Wyatt, RT, Kwong, PD, Mascola, JR
Publicado em 2009

NMR spectroscopy of HIV-1 gp120 outer domain

Por Sastry, M, Xu, L, Bhattacharya, S, Nabel, GJ, Bewley, CA, Kwong, PD
Publicado em 2012

P13-01. Crystal structure and function of a monoclonal antibody against primate CD4 that blocks HIV/SIV infection

Por Pegu, A, Boyington, JC, Kong, W, Shi, W, Kwong, PD, Nabel, GJ
Publicado em 2009

P04-38. Crystal structure of gp120 in complex with the CD4-binding-site antibody b13 suggests precise targeting is needed for neutralization

Por Zhou, T, Yang, Z, Xu, L, Hessell, AJ, Burton, DR, Nabel, GJ, Kwong, PD
Publicado em 2009

Structural definition for a new modality of broad and potent antibody neutralization at the CD4-binding site on HIV-1 gp120

Por Zhou, T, Moquin, S, Lynch, R, Wu, X, Zhu, J, Yang, Y, Zhang, B, Mascola, JR, Kwong, PD
Publicado em 2012

P12-12. Analysis of antibody and B cell responses following inoculation with computationally designed HIV-1 2F5 epitope scaffold proteins

Por Dosenovic, P, Guenaga, J, Ofek, G, Baker, D, Schief, W, Kwong, PD, Hedestam, GB Karlsson, Wyatt, RT
Publicado em 2009

Recombinant Env proteins that bind the quaternary-specific, V1/V2-directed PGT antibodies

Por Gorman, J, McLellan, J, Yang, Y, Zhou, T, Zhu, J, Bangaru, S, Bayless, N, Alff, P, Marshall, CP, Kwong, PD
Publicado em 2012

Partial germline reversions can increase VRC07 potency and breadth

Por Rudicell, RS, Georgiev, I, Yang, Z, O'Dell, S, Kwon, Y, Zhu, J, Wu, X, Kwong, PD, Mascola, JR, Nabel, GJ
Publicado em 2012

Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site

Por Dai, K, Boyington, JC, Shi, W, Schmidt, SD, Georgiev, I, Lingwood, D, Kwong, PD, Mascola, JR, Yang, Z, Nabel, GJ
Publicado em 2012

Structure-guided modification and optimization of antibody VRC07

Por Kwon Y, Georgiev I, O'Dell S, Shi W, Chuang G, Yang Y, Zhang B, Zhu J, Nabel GJ, Mascola JR, Kwong PD
Publicado em 2012-09-01

454 pyrosequencing and bioinformatics analysis of the lineage of the broad and potent gp41-directed antibody 10e8

Por Ofek, G, Zhu, J, Yang, Y, Zhang, B, Mckee, K, Louder, M, Huang, J, Laub, L, Connors, M, Mascola, J, Kwong, PD
Publicado em 2012

V1/V2-directed antibodies elicited in RV144 vaccinees bind to a structurally polymorphic site

Por McLellan, JS, Gorman, J, Bonsignori, M, Hwang, K, Liao, H, Rerks-Ngarm, S, Nitayaphan, S, Michael, NL, Kim, JH, Haynes, BF, Kwong, PD
Publicado em 2012

Structure-guided modification and optimization of antibody VRC07

Por Kwon, Y, Georgiev, I, O'Dell, S, Shi, W, Chuang, G, Yang, Y, Zhang, B, Zhu, J, Nabel, GJ, Mascola, JR, Kwong, PD
Publicado em 2012

Structural comparison of somatically related PG9 and PG16 in complex with their epitope reveals differences in glycan recognition

Por Pancera, M, McLellan, JS, Shahzad-ul-Hussan, S, Doria-Rose, N, Zhang, B, Yang, Y, Burton, DR, Koff, WC, Bewley, CA, Kwong, PD
Publicado em 2012

Structural definition of a novel CD4-induced epitope that is targeted by a single-headed immunoglobulin to effect broad and potent HIV neutralization

Por Acharya, P, Luongo, TS, Matz, J, Schmidt, SD, Chuang, G, Georgiev, I, Kessler, P, Yang, Y, Chames, P, Martin, L, Mascola, JR, Kwong, PD
Publicado em 2012

Characteristics of HIV-1 gp120 molecules that bind ancestor, intermediate and mature forms of VRC01-like antibodies

Por Joyce, M, Zhang, B, Zhou, T, Moquin, S, Wu, X, Louder, M, Zhang, Z, Georgiev, I, Zhu, J, Shapiro, L, Mascola, JR, Nabel, GJ, Kwong, PD
Publicado em 2012

P04-43. Neutralizing antibody responses against conformational envelope epitopes in early HIV-1 infection

Por Hahn BH, Yang Y, Wang S, Li H, Salazar M, Salazar-Gonzales J, McLellan J, Decker J, Keele BF, Bar KJ, Kwong PD, Shaw GM
Publicado em 2009-10-01

P04-43. Neutralizing antibody responses against conformational envelope epitopes in early HIV-1 infection

Por Bar, KJ, Keele, BF, Decker, J, McLellan, J, Salazar-Gonzales, J, Salazar, M, Li, H, Wang, S, Yang, Y, Hahn, BH, Kwong, PD, Shaw, GM
Publicado em 2009

Design of epitope-specific probes for sera analysis and antibody isolation

Por Georgiev I, Acharya P, Schmidt SD, Li Y, Wycuff D, Ofek G, Doria-Rose N, Luongo TS, Yang Y, Zhou T, Donald BR, Mascola JR, Kwong PD
Publicado em 2012-09-01