Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation

Por Tang, Matthew Y., Vranas, Marta, Krahn, Andrea I., Pundlik, Shayal, Trempe, Jean- François, Fon, Edward A.
Publicado no Nat Commun (2017)

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

Por McLelland, Gian-Luca, Goiran, Thomas, Yi, Wei, Dorval, Geneviève, Chen, Carol X, Lauinger, Nadine D, Krahn, Andrea I, Valimehr, Sepideh, Rakovic, Aleksandar, Rouiller, Isabelle, Durcan, Thomas M, Trempe, Jean-François, Fon, Edward A
Publicado no eLife (2018)