First-in-human studies of seletalisib, an orally bioavailable small-molecule PI3Kδ inhibitor for the treatment of immune and inflammatory diseases

Por Helmer, Eric, Watling, Mark, Jones, Emma, Tytgat, Dominique, Jones, Mark, Allen, Rodger, Payne, Andrew, Koch, Annelize, Healy, Eugene
Publicado no Eur J Clin Pharmacol (2017)

Use of Entero-Test, a simple approach for non-invasive clinical evaluation of the biliary disposition of drugs

Por Guiney, William J, Beaumont, Claire, Thomas, Steve R, Robertson, Darren C, McHugh, Simon M, Koch, Annelize, Richards, Duncan
Publicado em 2011

Neuroendocrine and sympathetic responses to an orexin receptor antagonist, SB-649868, and Alprazolam following insulin-induced hypoglycemia in humans

Por Patel, Ameera X., Miller, Sam R., Nathan, Pradeep J., Kanakaraj, Ponmani, Napolitano, Antonella, Lawrence, Philip, Koch, Annelize, Bullmore, Edward T.
Publicado em 2014

GP2015, a proposed etanercept biosimilar: Pharmacokinetic similarity to its reference product and comparison of its autoinjector device with prefilled syringes

Por von Richter, Oliver, Skerjanec, Andrej, Afonso, Miguel, Sanguino Heinrich, Sabine, Poetzl, Johann, Woehling, Heike, Velinova, Maria, Koch, Annelize, Kollins, Dmitrij, Macke, Lars, Wuerth, Guido
Publicado no Br J Clin Pharmacol (2016)

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach

Por McHugh, Simon M., Roman, Shilina, Davis, Bill, Koch, Annelize, Pickett, Alison M., Richardson, Jill C., Miller, Sam R., Wetten, Sally, Cox, Charles J., Karpe, Fredrik, Todd, John A., Bullmore, Edward T.
Publicado em 2012

Neural and Behavioral Effects of a Novel Mu Opioid Receptor Antagonist in Binge-Eating Obese People

Por Cambridge, Victoria C., Ziauddeen, Hisham, Nathan, Pradeep J., Subramaniam, Naresh, Dodds, Chris, Chamberlain, Samuel R., Koch, Annelize, Maltby, Kay, Skeggs, Andrew L., Napolitano, Antonella, Farooqi, I. Sadaf, Bullmore, Edward T., Fletcher, Paul C.
Publicado em 2013