Coenzyme Q10 Levels Are Decreased in the Cerebellum of Multiple-System Atrophy Patients

Por Schottlaender, Lucia V., Bettencourt, Conceição, Kiely, Aoife P., Chalasani, Annapurna, Neergheen, Viruna, Holton, Janice L., Hargreaves, Iain, Houlden, Henry
Publicado no PLoS One (2016)

Immunohistochemical and Molecular Investigations Show Alteration in the Inflammatory Profile of Multiple System Atrophy Brain

Por Kiely, Aoife P, Murray, Christina E, Foti, Sandrine C, Benson, Bridget C, Courtney, Robert, Strand, Catherine, Lashley, Tammaryn, Holton, Janice L
Publicado no J Neuropathol Exp Neurol (2018)

Neuropathological features of genetically confirmed DYT1 dystonia: investigating disease-specific inclusions

Por Paudel, Reema, Kiely, Aoife, Li, Abi, Lashley, Tammaryn, Bandopadhyay, Rina, Hardy, John, Jinnah, Hyder A, Bhatia, Kailash, Houlden, Henry, Holton, Janice L
Publicado no Acta Neuropathol Commun (2014)

α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy?

Por Kiely, Aoife P., Asi, Yasmine T., Kara, Eleanna, Limousin, Patricia, Ling, Helen, Lewis, Patrick, Proukakis, Christos, Quinn, Niall, Lees, Andrew J., Hardy, John, Revesz, Tamas, Houlden, Henry, Holton, Janice L.
Publicado em 2013

The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells...

Por Fares, Mohamed-Bilal, Ait-Bouziad, Nadine, Dikiy, Igor, Mbefo, Martial K., Jovičić, Ana, Kiely, Aoife, Holton, Janice L., Lee, Seung-Jae, Gitler, Aaron D., Eliezer, David, Lashuel, Hilal A.
Publicado em 2014

Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation

Por Kiely, Aoife P., Ling, Helen, Asi, Yasmine T., Kara, Eleanna, Proukakis, Christos, Schapira, Anthony H., Morris, Huw R., Roberts, Helen C., Lubbe, Steven, Limousin, Patricia, Lewis, Patrick A., Lees, Andrew J., Quinn, Niall, Hardy, John, Love, Seth, Revesz, Tamas, Houlden, Henry, Holton, Janice L.
Publicado no Mol Neurodegener (2015)

A 6.4MB duplication of the alpha-synuclein locus causing fronto-temporal dementia and parkinsonism - phenotype-genotype correlations

Por Kara, Eleanna, Kiely, Aoife P, Proukakis, Christos, Giffin, Nicola, Love, Seth, Hehir, Jason, Rantell, Khadija, Pandraud, Amelie, Hernandez, Dena G, Nacheva, Elizabeth, Pittman, Alan M, Nalls, Mike A, Singleton, Andrew B, Revesz, Tamas, Bhatia, Kailash P, Quinn, Niall, Hardy, John, Holton, Janice L, Houlden, Henry
Publicado no JAMA Neurol (2014)