Discovery of PEGylated 6-Benzhydryl-4-amino-quinazolines as Peripherally Restricted CB(1)R Inverse Agonists

af Zhang, Yue-Mei, Greco, Michael, Le Blanc, Tonya, Lang, Wensheng, Kauffman, Jack, Masucci, John, Murray, William V., Demarest, Keith, Macielag, Mark Joseph
Udgivet i ACS Med Chem Lett (2020)

Discovery of a Novel Series of Pyridone-Based EP3 Antagonists for the Treatment of Type 2 Diabetes

af Zhang, Xuqing, Zhu, Bin, Guo, Lili, Bakaj, Ivona, Rankin, Matthew, Ho, George, Kauffman, Jack, Lee, Seunghun P., Norquay, Lisa, Macielag, Mark J.
Udgivet i ACS Med Chem Lett (2021)

Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes

af Zhang, Xuqing, Wall, Mark, Sui, Zhihua, Kauffman, Jack, Hou, Cuifen, Chen, Cailin, Du, Fuyong, Kirchner, Thomas, Liang, Yin, Johnson, Dana L., Murray, William V., Demarest, Keith
Udgivet i ACS Med Chem Lett (2017)