Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies

door Lu, Tyler M., Barcia Durán, José Gabriel, Houghton, Sean, Rafii, Shahin, Redmond, David, Lis, Raphaël
Gepubliceerd in Front Physiol (2021)

Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice

door Barcia Durán, José Gabriel, Lu, Tyler, Houghton, Sean, Geng, Fuqiang, Schreiner, Ryan, Xiang, Jenny, Rafii, Shahin, Redmond, David, Lis, Raphaël
Gepubliceerd in Commun Biol (2021)

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

door Choi, Hyejin, Deng, Jiehui, Li, Shuai, Silk, Tarik, Dong, Lauren, Brea, Elliott J., Houghton, Sean, Redmond, David, Zhong, Hong, Boiarsky, Jonathan, Akbay, Esra A., Smith, Paul D., Merghoub, Taha, Wong, Kwok-Kin, Wolchok, Jedd D.
Gepubliceerd in Cell Rep (2019)

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

door Lu, Tyler M., Houghton, Sean, Magdeldin, Tarig, Durán, José Gabriel Barcia, Minotti, Andrew P., Snead, Amanda, Sproul, Andrew, Nguyen, Duc-Huy T., Xiang, Jenny, Fine, Howard A., Rosenwaks, Zev, Studer, Lorenz, Rafii, Shahin, Agalliu, Dritan, Redmond, David, Lis, Raphaël
Gepubliceerd in Proc Natl Acad Sci U S A (2021)

Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis

door Gomez-Salinero, Jesus M, Itkin, Tomer, Houghton, Sean, Badwe, Chaitanya, Lin, Yang, Kalna, Viktoria, Dufton, Neil, Peghaire, Claire R, Yokoyama, Masataka, Wingo, Matthew, Lu, Tyler M., Li, Ge, Xiang, Jenny Zhaoying, Hsu, Yen-Michael Sheng, Redmond, David, Schreiner, Ryan, Birdsey, Graeme M, Randi, Anna M, Rafii, Shahin
Gepubliceerd in Nat Cardiovasc Res (2022)

Reversal of emphysema by restoration of pulmonary endothelial cells

door Hisata, Shu, Racanelli, Alexandra C., Kermani, Pouneh, Schreiner, Ryan, Houghton, Sean, Palikuqi, Brisa, Kunar, Balvir, Zhou, Aiyuan, McConn, Keith, Capili, Allyson, Redmond, David, Nolan, Daniel J., Ginsberg, Michael, Ding, Bi-Sen, Martinez, Fernando J., Scandura, Joseph M., Cloonan, Suzanne M., Rafii, Shahin, Choi, Augustine M.K.
Gepubliceerd in J Exp Med (2021)

In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors

door Khalil, Danny N., Suek, Nathan, Campesato, Luis Felipe, Budhu, Sadna, Redmond, David, Samstein, Robert M., Krishna, Chirag, Panageas, Katherine S., Capanu, Marinela, Houghton, Sean, Hirschhorn, Daniel, Zappasodi, Roberta, Giese, Rachel, Gasmi, Billel, Schneider, Michael, Gupta, Aditi, Harding, James J., Moral, John Alec, Balachandran, Vinod P., Wolchok, Jedd D., Merghoub, Taha
Gepubliceerd in J Clin Invest (2019)

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2

door Chen, Shuibing, Yang, Liuliu, Nilsson-Payant, Benjamin, Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Horiuchi, Shu, Acklin, Joshua, Lim, Jean, Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David, Schwartz, Robert, tenOever, Benjamin, Evans, Todd
Gepubliceerd in Res Sq (2020)

An Immuno-Cardiac Model for Macrophage-mediated Inflammation in COVID-19 Hearts

door Yang, Liuliu, Han, Yuling, Jaffré, Fabrice, Nilsson-Payant, Benjamin E., Bram, Yaron, Wang, Pengfei, Zhu, Jiajun, Zhang, Tuo, Redmond, David, Houghton, Sean, Uhl, Skyler, Borczuk, Alain, Huang, Yaoxing, Richardson, Chanel, Chandar, Vasuretha, Acklin, Joshua A, Lim, Jean K., Chen, Zhengming, Xiang, Jenny, Ho, David D., tenOever, Benjamin R., Schwartz, Robert E., Evans, Todd, Chen, Shuibing
Gepubliceerd in Circ Res (2021)

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

door Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Gepubliceerd in Stem Cell Reports (2021)

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

door Han, Yuling, Yang, Liuliu, Duan, Xiaohua, Duan, Fuyu, Nilsson-Payant, Benjamin E., Yaron, Tomer M., Wang, Pengfei, Tang, Xuming, Zhang, Tuo, Zhao, Zeping, Bram, Yaron, Redmond, David, Houghton, Sean, Nguyen, Duc, Xu, Dong, Wang, Xing, Uhl, Skyler, Huang, Yaoxing, Johnson, Jared L., Xiang, Jenny, Wang, Hui, Pan, Fong Cheng, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Evans, Todd, Schwartz, Robert E., Chen, Huanhuan Joyce, Chen, Shuibing
Gepubliceerd in bioRxiv (2020)

Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids

door Han, Yuling, Duan, Xiaohua, Yang, Liuliu, Nilsson-Payant, Benjamin E., Wang, Pengfei, Duan, Fuyu, Tang, Xuming, Yaron, Tomer M., Zhang, Tuo, Uhl, Skyler, Bram, Yaron, Richardson, Chanel, Zhu, Jiajun, Zhao, Zeping, Redmond, David, Houghton, Sean, Nguyen, Duc-Huy T., Xu, Dong, Wang, Xing, Jessurun, Jose, Borczuk, Alain, Huang, Yaoxing, Johnson, Jared L., Liu, Yuru, Xiang, Jenny, Wang, Hui, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Pan, Fong Cheng, Evans, Todd, Chen, Huanhuan Joyce, Schwartz, Robert E., Chen, Shuibing
Gepubliceerd in Nature (2020)

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

door Yang, Liuliu, Han, Yuling, Nilsson-Payant, Benjamin E., Gupta, Vikas, Wang, Pengfei, Duan, Xiaohua, Tang, Xuming, Zhu, Jiajun, Zhao, Zeping, Jaffré, Fabrice, Zhang, Tuo, Kim, Tae Wan, Harschnitz, Oliver, Redmond, David, Houghton, Sean, Liu, Chengyang, Naji, Ali, Ciceri, Gabriele, Guttikonda, Sudha, Bram, Yaron, Nguyen, Duc-Huy T., Cioffi, Michele, Chandar, Vasuretha, Hoagland, Daisy A., Huang, Yaoxing, Xiang, Jenny, Wang, Hui, Lyden, David, Borczuk, Alain, Chen, Huanhuan Joyce, Studer, Lorenz, Pan, Fong Cheng, Ho, David D., tenOever, Benjamin R., Evans, Todd, Schwartz, Robert E., Chen, Shuibing
Gepubliceerd in Cell Stem Cell (2020)