Human Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells: Current Controversies

por Lu, Tyler M., Barcia Durán, José Gabriel, Houghton, Sean, Rafii, Shahin, Redmond, David, Lis, Raphaël
Publicado en Front Physiol (2021)

Endothelial Jak3 expression enhances pro-hematopoietic angiocrine function in mice

por Barcia Durán, José Gabriel, Lu, Tyler, Houghton, Sean, Geng, Fuqiang, Schreiner, Ryan, Xiang, Jenny, Rafii, Shahin, Redmond, David, Lis, Raphaël
Publicado en Commun Biol (2021)

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

por Choi, Hyejin, Deng, Jiehui, Li, Shuai, Silk, Tarik, Dong, Lauren, Brea, Elliott J., Houghton, Sean, Redmond, David, Zhong, Hong, Boiarsky, Jonathan, Akbay, Esra A., Smith, Paul D., Merghoub, Taha, Wong, Kwok-Kin, Wolchok, Jedd D.
Publicado en Cell Rep (2019)

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

por Lu, Tyler M., Houghton, Sean, Magdeldin, Tarig, Durán, José Gabriel Barcia, Minotti, Andrew P., Snead, Amanda, Sproul, Andrew, Nguyen, Duc-Huy T., Xiang, Jenny, Fine, Howard A., Rosenwaks, Zev, Studer, Lorenz, Rafii, Shahin, Agalliu, Dritan, Redmond, David, Lis, Raphaël
Publicado en Proc Natl Acad Sci U S A (2021)

Cooperative ETS Transcription Factors Enforce Adult Endothelial Cell Fate and Cardiovascular Homeostasis

por Gomez-Salinero, Jesus M, Itkin, Tomer, Houghton, Sean, Badwe, Chaitanya, Lin, Yang, Kalna, Viktoria, Dufton, Neil, Peghaire, Claire R, Yokoyama, Masataka, Wingo, Matthew, Lu, Tyler M., Li, Ge, Xiang, Jenny Zhaoying, Hsu, Yen-Michael Sheng, Redmond, David, Schreiner, Ryan, Birdsey, Graeme M, Randi, Anna M, Rafii, Shahin
Publicado en Nat Cardiovasc Res (2022)

Reversal of emphysema by restoration of pulmonary endothelial cells

por Hisata, Shu, Racanelli, Alexandra C., Kermani, Pouneh, Schreiner, Ryan, Houghton, Sean, Palikuqi, Brisa, Kunar, Balvir, Zhou, Aiyuan, McConn, Keith, Capili, Allyson, Redmond, David, Nolan, Daniel J., Ginsberg, Michael, Ding, Bi-Sen, Martinez, Fernando J., Scandura, Joseph M., Cloonan, Suzanne M., Rafii, Shahin, Choi, Augustine M.K.
Publicado en J Exp Med (2021)

In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors

por Khalil, Danny N., Suek, Nathan, Campesato, Luis Felipe, Budhu, Sadna, Redmond, David, Samstein, Robert M., Krishna, Chirag, Panageas, Katherine S., Capanu, Marinela, Houghton, Sean, Hirschhorn, Daniel, Zappasodi, Roberta, Giese, Rachel, Gasmi, Billel, Schneider, Michael, Gupta, Aditi, Harding, James J., Moral, John Alec, Balachandran, Vinod P., Wolchok, Jedd D., Merghoub, Taha
Publicado en J Clin Invest (2019)

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2

por Chen, Shuibing, Yang, Liuliu, Nilsson-Payant, Benjamin, Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Horiuchi, Shu, Acklin, Joshua, Lim, Jean, Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David, Schwartz, Robert, tenOever, Benjamin, Evans, Todd
Publicado en Res Sq (2020)

An Immuno-Cardiac Model for Macrophage-mediated Inflammation in COVID-19 Hearts

por Yang, Liuliu, Han, Yuling, Jaffré, Fabrice, Nilsson-Payant, Benjamin E., Bram, Yaron, Wang, Pengfei, Zhu, Jiajun, Zhang, Tuo, Redmond, David, Houghton, Sean, Uhl, Skyler, Borczuk, Alain, Huang, Yaoxing, Richardson, Chanel, Chandar, Vasuretha, Acklin, Joshua A, Lim, Jean K., Chen, Zhengming, Xiang, Jenny, Ho, David D., tenOever, Benjamin R., Schwartz, Robert E., Evans, Todd, Chen, Shuibing
Publicado en Circ Res (2021)

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

por Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Publicado en Stem Cell Reports (2021)

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

por Han, Yuling, Yang, Liuliu, Duan, Xiaohua, Duan, Fuyu, Nilsson-Payant, Benjamin E., Yaron, Tomer M., Wang, Pengfei, Tang, Xuming, Zhang, Tuo, Zhao, Zeping, Bram, Yaron, Redmond, David, Houghton, Sean, Nguyen, Duc, Xu, Dong, Wang, Xing, Uhl, Skyler, Huang, Yaoxing, Johnson, Jared L., Xiang, Jenny, Wang, Hui, Pan, Fong Cheng, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Evans, Todd, Schwartz, Robert E., Chen, Huanhuan Joyce, Chen, Shuibing
Publicado en bioRxiv (2020)

Identification of SARS-CoV-2 Inhibitors using Lung and Colonic Organoids

por Han, Yuling, Duan, Xiaohua, Yang, Liuliu, Nilsson-Payant, Benjamin E., Wang, Pengfei, Duan, Fuyu, Tang, Xuming, Yaron, Tomer M., Zhang, Tuo, Uhl, Skyler, Bram, Yaron, Richardson, Chanel, Zhu, Jiajun, Zhao, Zeping, Redmond, David, Houghton, Sean, Nguyen, Duc-Huy T., Xu, Dong, Wang, Xing, Jessurun, Jose, Borczuk, Alain, Huang, Yaoxing, Johnson, Jared L., Liu, Yuru, Xiang, Jenny, Wang, Hui, Cantley, Lewis C., tenOever, Benjamin R., Ho, David D., Pan, Fong Cheng, Evans, Todd, Chen, Huanhuan Joyce, Schwartz, Robert E., Chen, Shuibing
Publicado en Nature (2020)

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

por Yang, Liuliu, Han, Yuling, Nilsson-Payant, Benjamin E., Gupta, Vikas, Wang, Pengfei, Duan, Xiaohua, Tang, Xuming, Zhu, Jiajun, Zhao, Zeping, Jaffré, Fabrice, Zhang, Tuo, Kim, Tae Wan, Harschnitz, Oliver, Redmond, David, Houghton, Sean, Liu, Chengyang, Naji, Ali, Ciceri, Gabriele, Guttikonda, Sudha, Bram, Yaron, Nguyen, Duc-Huy T., Cioffi, Michele, Chandar, Vasuretha, Hoagland, Daisy A., Huang, Yaoxing, Xiang, Jenny, Wang, Hui, Lyden, David, Borczuk, Alain, Chen, Huanhuan Joyce, Studer, Lorenz, Pan, Fong Cheng, Ho, David D., tenOever, Benjamin R., Evans, Todd, Schwartz, Robert E., Chen, Shuibing
Publicado en Cell Stem Cell (2020)