Biochemical Assessment and Monitoring of Mitochondrial Disease

by Hargreaves, Iain P.
Published in J Clin Med (2018)

Coenzyme Q10 in Mitochondrial and Lysosomal Disorders

by Hargreaves, Iain P.
Published in J Clin Med (2021)

Coenzyme Q10 and Immune Function: An Overview

by Mantle, David, Heaton, Robert A., Hargreaves, Iain P.
Published in Antioxidants (Basel) (2021)

Assessment of Mitochondrial Dysfunction in Experimental Autoimmune Encephalomyelitis (EAE) Models of Multiple Sclerosis

by Ng, Xiulin, Sadeghian, Mona, Heales, Simon, Hargreaves, Iain P.
Published in Int J Mol Sci (2019)

Biochemical Diagnosis of Coenzyme Q(10) Deficiency

by Yubero, Delia, Montero, Raquel, Artuch, Rafael, Land, John M., Heales, Simon J.R., Hargreaves, Iain P.
Published 2014

Evidence of Oxidative Stress and Secondary Mitochondrial Dysfunction in Metabolic and Non-Metabolic Disorders

by Stepien, Karolina M., Heaton, Robert, Rankin, Scott, Murphy, Alex, Bentley, James, Sexton, Darren, Hargreaves, Iain P.
Published in J Clin Med (2017)

The Effect of Organophosphate Exposure on Neuronal Cell Coenzyme Q(10) Status

by Turton, Nadia, Heaton, Robert A., Ismail, Fahima, Roberts, Sioned, Nelder, Sian, Phillips, Sue, Hargreaves, Iain P.
Published in Neurochem Res (2020)

The Effect of Methylmalonic Acid Treatment on Human Neuronal Cell Coenzyme Q(10) Status and Mitochondrial Function

by Proctor, Emma C., Turton, Nadia, Boan, Elle Jo, Bennett, Emily, Philips, Suzannah, Heaton, Robert A., Hargreaves, Iain P.
Published in Int J Mol Sci (2020)

Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats

by Tarry-Adkins, Jane L., Fernandez-Twinn, Denise S., Chen, Jian Hua, Hargreaves, Iain P., Neergheen, Viruna, Aiken, Catherine E., Ozanne, Susan E.
Published in Dis Model Mech (2016)

Nutritional programming of coenzyme Q: potential for prevention and intervention?

by Tarry-Adkins, Jane L., Fernandez-Twinn, Denise S., Chen, Jian-Hua, Hargreaves, Iain P., Martin-Gronert, Malgorzata S., McConnell, Josie M., Ozanne, Susan E.
Published in FASEB J (2014)

CoQ(10) Deficient Endothelial Cell Culture Model for the Investigation of CoQ(10) Blood–Brain Barrier Transport

by Wainwright, Luke, Hargreaves, Iain P., Georgian, Ana R., Turner, Charles, Dalton, R. Neil, Abbott, N. Joan, Heales, Simon J. R., Preston, Jane E.
Published in J Clin Med (2020)

Coenzyme Q(10) Prevents Insulin Signaling Dysregulation and Inflammation Prior to Development of Insulin Resistance in Male Offspring of a Rat Model of Poor Maternal Nutrition and...

by Tarry-Adkins, Jane L., Fernandez-Twinn, Denise S., Madsen, Ralitsa, Chen, Jian-Hua, Carpenter, Asha, Hargreaves, Iain P., McConnell, Josie M., Ozanne, Susan E.
Published in Endocrinology (2015)

Altered skeletal muscle insulin signaling and mitochondrial complex II-III linked activity in adult offspring of obese mice

by Shelley, Piran, Martin-Gronert, Malgorzata S., Rowlerson, Anthea, Poston, Lucilla, Heales, S. J. R., Hargreaves, Iain P., McConnell, Josie M., Ozanne, Susan E., Fernandez-Twinn, Denise S.
Published 2009

OP55 BIOCHEMICAL ANALYSIS COMBINED WITH 3D STRUCTURAL PROTEIN MODELLING IDENTIFIES THE ROLE OF SPECIFIC MITOCHONDRIAL MUTATIONS IN GBM

by Keatley, Kathleen, Polyzoidis, Stavros, Ashkan, Keyoumars, Heales, Simon J., Fillmore, Helen L., Hargreaves, Iain P., McGeehan, John E., Lloyd, Rhiannon E., Pilkington, Geoffrey J.
Published in Neuro Oncol (2015)

Coenzyme Q(10) prevents hepatic fibrosis, inflammation, and oxidative stress in a male rat model of poor maternal nutrition and accelerated postnatal growth(1)

by Tarry-Adkins, Jane L, Fernandez-Twinn, Denise S, Hargreaves, Iain P, Neergheen, Viruna, Aiken, Catherine E, Martin-Gronert, Malgorzata S, McConnell, Josie M, Ozanne, Susan E
Published in Am J Clin Nutr (2016)

Coenzyme Q(10) prevents accelerated cardiac aging in a rat model of poor maternal nutrition and accelerated postnatal growth()

by Tarry-Adkins, Jane L., Blackmore, Heather L., Martin-Gronert, Malgorzata S., Fernandez-Twinn, Denise S., McConnell, Josie M., Hargreaves, Iain P., Giussani, Dino A., Ozanne, Susan E.
Published 2013

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

by Osellame, Laura D., Rahim, Ahad A., Hargreaves, Iain P., Gegg, Matthew E., Richard-Londt, Angela, Brandner, Sebastian, Waddington, Simon N., Schapira, Anthony H.V., Duchen, Michael R.
Published 2013

Maternal but not fetoplacental health can be improved by metformin in a murine diet-induced model of maternal obesity and glucose intolerance

by Hufnagel, Antonia, Fernandez-Twinn, Denise S, Blackmore, Heather L, Ashmore, Thomas J, Heaton, Robert A, Jenkins, Benjamin, Koulman, Albert, Hargreaves, Iain P, Aiken, Catherine E, Ozanne, Susan E
Published in J Physiol (2022)

Using a quantitative quadruple immunofluorescent assay to diagnose isolated mitochondrial Complex I deficiency

by Ahmed, Syeda T., Alston, Charlotte L., Hopton, Sila, He, Langping, Hargreaves, Iain P., Falkous, Gavin, Oláhová, Monika, McFarland, Robert, Turnbull, Doug M., Rocha, Mariana C., Taylor, Robert W.
Published in Sci Rep (2017)

Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease()

by Dunn, Laura, Allen, George FG., Mamais, Adamantios, Ling, Helen, Li, Abi, Duberley, Kate E., Hargreaves, Iain P., Pope, Simon, Holton, Janice L., Lees, Andrew, Heales, Simon J., Bandopadhyay, Rina
Published 2014