In vivo uptake of antisense oligonucleotide drugs predicted by ab initio quantum mechanical calculations

Por Hansen, Henrik Frydenlund, Albaek, Nanna, Hansen, Bo Rode, Shim, Irene, Bohr, Henrik, Koch, Troels
Publicado no Sci Rep (2021)

Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-mediated Silencing in Mammalian Cells

Por Castanotto, Daniela, Lin, Min, Kowolik, Claudia, Koch, Troels, Hansen, Bo Rode, Oerum, Henrik, Stein, Cy A
Publicado no Mol Ther (2016)

A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells

Por Castanotto, Daniela, Lin, Min, Kowolik, Claudia, Wang, LiAnn, Ren, Xiao-Qin, Soifer, Harris S., Koch, Troels, Hansen, Bo Rode, Oerum, Henrik, Armstrong, Brian, Wang, Zhigang, Bauer, Paul, Rossi, John, Stein, C.A.
Publicado no Nucleic Acids Res (2015)

A Multifunctional LNA Oligonucleotide-Based Strategy Blocks AR Expression and Transactivation Activity in PCa Cells

Por Castanotto, Daniela, Zhang, Xiaowei, Rüger, Jacqueline, Alluin, Jessica, Sharma, Ritin, Pirrotte, Patrick, Joenson, Lars, Ioannou, Silvia, Nelson, Michael S., Vikeså, Jonas, Hansen, Bo Rode, Koch, Troels, Jensen, Mads Aaboe, Rossi, John J., Stein, Cy A.
Publicado no Mol Ther Nucleic Acids (2020)