Exploring the Active Site of Phenylethanolamine N-Methyltransferase with 1,2,3,4-Tetrahydrobenz[h]isoquinoline Inhibitors(1)

Por Grunewald, Gary L., Seim, Mitchell R., Regier, Rachel C., Criscione, Kevin R.
Publicado em 2006

Application of the Goldilocks Effect to the Design of Potent and Selective Inhibitors of Phenylethanolamine N-Methyltransferase: Balancing pK(a) and Steric Effects in the Optimizat...

Por Grunewald, Gary L., Seim, Mitchell R., Lu, Jian, Makboul, Mariam, Criscione, Kevin R.
Publicado em 2006

Synthesis of 4,5,6,7-Tetrahydrothieno[3,2-c]pyridines and Comparison with Their Isosteric 1,2,3,4-Tetrahydroisoquinolines as Inhibitors of Phenylethanolamine N-Methyltransferase

Por Grunewald, Gary L., Seim, Mitchell R., Bhat, Seema R., Wilson, Marc E., Criscione, Kevin R.
Publicado em 2007

Time-dependent inactivation of human phenylethanolamine N-methyltransferase by 7-isothiocyanatotetrahydroisoquinoline

Por Wu, Qian, Caine, Joanne M., Thomson, Stuart A., Slavica, Meri, Grunewald, Gary L., McLeish, Michael J.
Publicado em 2009