Germline missense pathogenic variants in the BRCA1 BRCT domain, p.Gly1706Glu and p.Ala1708Glu, increase cellular sensitivity to PARP inhibitor olaparib by a dominant negative effec...

Por Vaclová, Tereza, Woods, Nicholas T., Megías, Diego, Gomez-Lopez, Sergio, Setién, Fernando, García Bueno, José María, Macías, José Antonio, Barroso, Alicia, Urioste, Miguel, Esteller, Manel, Monteiro, Alvaro N.A., Benítez, Javier, Osorio, Ana
Publicado no Hum Mol Genet (2016)