NMR studies of novel inhibitors bound to farnesyl-protein transferase.

Por Koblan, K. S., Culberson, J. C., Desolms, S. J., Giuliani, E. A., Mosser, S. D., Omer, C. A., Pitzenberger, S. M., Bogusky, M. J.
Publicado em 1995

Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.

Por Prendergast, G C, Davide, J P, deSolms, S J, Giuliani, E A, Graham, S L, Gibbs, J B, Oliff, A, Kohl, N E
Publicado em 1994