Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2′ Moiety

von Hu, Zilun, Wong, Pancras C., Gilligan, Paul J., Han, Wei, Pabbisetty, Kumar B., Bozarth, Jeffrey M., Crain, Earl J., Harper, Timothy, Luettgen, Joseph M., Myers, Joseph E., Ramamurthy, Vidhyashankar, Rossi, Karen A., Sheriff, Steven, Watson, Carol A., Wei, Anzi, Zheng, Joanna J., Seiffert, Dietmar A., Wexler, Ruth R., Quan, Mimi L.
Veröffentlicht in ACS Med Chem Lett (2015)