A phase Ib study of pictilisib (GDC-0941) in combination with paclitaxel, with and without bevacizumab or trastuzumab, and with letrozole in advanced breast cancer

by Schöffski, Patrick, Cresta, Sara, Mayer, Ingrid A., Wildiers, Hans, Damian, Silvia, Gendreau, Steven, Rooney, Isabelle, Morrissey, Kari M., Spoerke, Jill M., Ng, Vivian W., Singel, Stina M., Winer, Eric
Published in Breast Cancer Res (2018)

Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant

by Spoerke, Jill M., Gendreau, Steven, Walter, Kimberly, Qiu, Jiaheng, Wilson, Timothy R., Savage, Heidi, Aimi, Junko, Derynck, Mika K., Chen, Meng, Chan, Iris T., Amler, Lukas C., Hampton, Garret M., Johnston, Stephen, Krop, Ian, Schmid, Peter, Lackner, Mark R.
Published in Nat Commun (2016)

Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis

by Greene, Stephanie B., Dago, Angel E., Leitz, Laura J., Wang, Yipeng, Lee, Jerry, Werner, Shannon L., Gendreau, Steven, Patel, Premal, Jia, Shidong, Zhang, Liangxuan, Tucker, Eric K., Malchiodi, Michael, Graf, Ryon P., Dittamore, Ryan, Marrinucci, Dena, Landers, Mark
Published in PLoS One (2016)

Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 tri...

by Krop, Ian E, Mayer, Ingrid A, Ganju, Vinod, Dickler, Maura, Johnston, Stephen, Morales, Serafin, Yardley, Denise A, Melichar, Bohuslav, Forero-Torres, Andres, Lee, Soo Chin, de Boer, Richard, Petrakova, Katarina, Vallentin, Susanne, Perez, Edith A, Piccart, Martine, Ellis, Matthew, Winer, Eric, Gendreau, Steven, Derynck, Mika, Lackner, Mark, Levy, Gallia, Qiu, Jiaheng, He, Jing, Schmid, Peter
Published in Lancet Oncol (2016)

Phase II Randomized Preoperative Window-of-Opportunity Study of the PI3K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor–Po...

by Schmid, Peter, Pinder, Sarah E., Wheatley, Duncan, Macaskill, Jane, Zammit, Charles, Hu, Jennifer, Price, Robert, Bundred, Nigel, Hadad, Sirwan, Shia, Alice, Sarker, Shah-Jalal, Lim, Louise, Gazinska, Patrycja, Woodman, Natalie, Korbie, Darren, Trau, Matt, Mainwaring, Paul, Gendreau, Steven, Lackner, Mark R., Derynck, Mika, Wilson, Timothy R., Butler, Hannah, Earl, Gemma, Parker, Peter, Purushotham, Arnie, Thompson, Alastair
Published in J Clin Oncol (2016)

Analytical Validation of a Hybrid Capture–Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA

by Clark, Travis A., Chung, Jon H., Kennedy, Mark, Hughes, Jason D., Chennagiri, Niru, Lieber, Daniel S., Fendler, Bernard, Young, Lauren, Zhao, Mandy, Coyne, Michael, Breese, Virginia, Young, Geneva, Donahue, Amy, Pavlick, Dean, Tsiros, Alyssa, Brennan, Timothy, Zhong, Shan, Mughal, Tariq, Bailey, Mark, He, Jie, Roels, Steven, Frampton, Garrett M., Spoerke, Jill M., Gendreau, Steven, Lackner, Mark, Schleifman, Erica, Peters, Eric, Ross, Jeffrey S., Ali, Siraj M., Miller, Vincent A., Gregg, Jeffrey P., Stephens, Philip J., Welsh, Allison, Otto, Geoff A., Lipson, Doron
Published in J Mol Diagn (2018)