Engineered BDNF producing cells as a potential treatment for neurologic disease

Por Deng, Peter, Anderson, Johnathon D., Yu, Abigail S., Annett, Geralyn, Fink, Kyle D., Nolta, Jan A.
Publicado no Expert Opin Biol Ther (2016)

Clinical trial perspective for adult and juvenile Huntington's disease using genetically-engineered mesenchymal stem cells

Por Deng, Peter, Torrest, Audrey, Pollock, Kari, Dahlenburg, Heather, Annett, Geralyn, Nolta, Jan A., Fink, Kyle D.
Publicado no Neural Regen Res (2016)

Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

Por Fink, Kyle D, Rossignol, Julien, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Bavar, Angela M, Clerc, Steven, Lowrance, Steven A, Song, Cheng, Lescaudron, Laurent, Dunbar, Gary L
Publicado em 2013

Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is depe...

Por Rossignol, Julien, Fink, Kyle D, Crane, Andrew T, Davis, Kendra K, Bombard, Matthew C, Clerc, Steven, Bavar, Angela M, Lowrance, Steven A, Song, Cheng, Witte, Steven, Lescaudron, Laurent, Dunbar, Gary L
Publicado no Stem Cell Res Ther (2015)

Intrastriatal Transplantation of Adenovirus-Generated Induced Pluripotent Stem Cells for Treating Neuropathological and Functional Deficits in a Rodent Model of Huntington’s Diseas...

Por Fink, Kyle D., Crane, Andrew T., Lévêque, Xavier, Dues, Dylan J., Huffman, Lucas D., Moore, Allison C., Story, Darren T., DeJonge, Rachel E., Antcliff, Aaron, Starski, Phillip A., Lu, Ming, Lescaudron, Laurent, Rossignol, Julien, Dunbar, Gary L.
Publicado em 2014

Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington's Disease Mouse Models

Por Pollock, Kari, Dahlenburg, Heather, Nelson, Haley, Fink, Kyle D, Cary, Whitney, Hendrix, Kyle, Annett, Geralyn, Torrest, Audrey, Deng, Peter, Gutierrez, Joshua, Nacey, Catherine, Pepper, Karen, Kalomoiris, Stefanos, D Anderson, Johnathon, McGee, Jeannine, Gruenloh, William, Fury, Brian, Bauer, Gerhard, Duffy, Alexandria, Tempkin, Theresa, Wheelock, Vicki, Nolta, Jan A
Publicado no Mol Ther (2016)

Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling

Por Anderson, Johnathon D., Johansson, Henrik J., Graham, Calvin S., Vesterlund, Mattias, Pham, Missy T., Bramlett, Charles S., Montgomery, Elizabeth N., Mellema, Matt S., Bardini, Renee L., Contreras, Zelenia, Hoon, Madeline, Bauer, Gerhard, Fink, Kyle D., Fury, Brian, Hendrix, Kyle J., Chedin, Frederic, El-Andaloussi, Samir, Hwang, Billie, Mulligan, Michael S., Lehtiö, Janne, Nolta, Jan A.
Publicado no Stem Cells (2016)