Identification of an UP element consensus sequence for bacterial promoters

por Estrem, Shawn T., Gaal, Tamas, Ross, Wilma, Gourse, Richard L.
Publicado 1998

Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase α subunit

por Estrem, Shawn T., Ross, Wilma, Gaal, Tamas, Chen, Z. W. Susan, Niu, Wei, Ebright, Richard H., Gourse, Richard L.
Publicado 1999

Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults

por Raue, Ulrika, Trappe, Todd A., Estrem, Shawn T., Qian, Hui-Rong, Helvering, Leah M., Smith, Rosamund C., Trappe, Scott
Publicado 2012

Reactivation of Mitogen-activated Protein Kinase (MAPK) Pathway by FGF Receptor 3 (FGFR3)/Ras Mediates Resistance to Vemurafenib in Human B-RAF V600E Mutant Melanoma

por Yadav, Vipin, Zhang, Xiaoyi, Liu, Jiangang, Estrem, Shawn, Li, Shuyu, Gong, Xue-Qian, Buchanan, Sean, Henry, James R., Starling, James J., Peng, Sheng-Bin
Publicado 2012

Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in pa...

por Wick, Antje, Desjardins, Annick, Suarez, Cristina, Forsyth, Peter, Gueorguieva, Ivelina, Burkholder, Tiana, Cleverly, Ann Louise, Estrem, Shawn T., Wang, Shuaicheng, Lahn, Michael M., Guba, Susan C., Capper, David, Rodon, Jordi
Publicado en Invest New Drugs (2020)

Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib

por Giannelli, Gianluigi, Santoro, Armando, Kelley, Robin K., Gane, Ed, Paradis, Valerie, Cleverly, Ann, Smith, Claire, Estrem, Shawn T., Man, Michael, Wang, Shuaicheng, Lahn, Michael M., Raymond, Eric, Benhadji, Karim A., Faivre, Sandrine
Publicado en PLoS One (2020)

Correction: Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib

por Giannelli, Gianluigi, Santoro, Armando, Kelley, Robin K., Gane, Ed, Paradis, Valerie, Cleverly, Ann, Smith, Claire, Estrem, Shawn T., Man, Michael, Wang, Shuaicheng, Lahn, Michael M., Raymond, Eric, Benhadji, Karim A., Faivre, Sandrine
Publicado en PLoS One (2021)

Clinical development of galunisertib (LY2157299 monohydrate), a small molecule inhibitor of transforming growth factor-beta signaling pathway

por Herbertz, Stephan, Sawyer, J Scott, Stauber, Anja J, Gueorguieva, Ivelina, Driscoll, Kyla E, Estrem, Shawn T, Cleverly, Ann L, Desaiah, Durisala, Guba, Susan C, Benhadji, Karim A, Slapak, Christopher A, Lahn, Michael M
Publicado en Drug Des Devel Ther (2015)

Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer

por Melisi, Davide, Garcia-Carbonero, Rocio, Macarulla, Teresa, Pezet, Denis, Deplanque, Gael, Fuchs, Martin, Trojan, Jorg, Oettle, Helmut, Kozloff, Mark, Cleverly, Ann, Smith, Claire, Estrem, Shawn T., Gueorguieva, Ivelina, Lahn, Michael M. F., Blunt, Al, Benhadji, Karim A., Tabernero, Josep
Publicado en Br J Cancer (2018)

Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced canc...

por Rodón, Jordi, Carducci, Michael, Sepulveda-Sánchez, Juan M., Azaro, Analía, Calvo, Emiliano, Seoane, Joan, Braña, Irene, Sicart, Elisabet, Gueorguieva, Ivelina, Cleverly, Ann, Pillay, N. Sokalingum, Desaiah, Durisala, Estrem, Shawn T., Paz-Ares, Luis, Holdhoff, Matthias, Blakeley, Jaishri, Lahn, Michael M., Baselga, Jose
Publicado en Invest New Drugs (2014)

First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma

por Rodon, Jordi, Carducci, Michael A., Sepulveda-Sánchez, Juan M, Azaro, Analia, Calvo, Emiliano, Seoane, Joan, Braña, Irene, Sicart, Elisabet, Gueorguieva, Ivelina, Cleverly, Ann L., Pillay, N. Sokalingum, Desaiah, Durisala, Estrem, Shawn T., Paz-Ares, Luis, Holdhoff, Matthias, Blakeley, Jaishri, Lahn, Michael M., Baselga, Jose
Publicado en Clin Cancer Res (2014)

Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer

por Melisi, Davide, Oh, Do-Youn, Hollebecque, Antoine, Calvo, Emiliano, Varghese, Anna, Borazanci, Erkut, Macarulla, Teresa, Merz, Valeria, Zecchetto, Camilla, Zhao, Yumin, Gueorguieva, Ivelina, Man, Michael, Gandhi, Leena, Estrem, Shawn T, Benhadji, Karim A, Lanasa, Mark C, Avsar, Emin, Guba, Susan C, Garcia-Carbonero, Rocio
Publicado en J Immunother Cancer (2021)

Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine

por Capper, David, von Deimling, Andreas, Brandes, Alba A., Carpentier, Antoine F., Kesari, Santosh, Sepulveda-Sanchez, Juan M., Wheeler, Helen R., Chinot, Olivier, Cher, Lawrence, Steinbach, Joachim P., Specenier, Pol, Rodon, Jordi, Cleverly, Ann, Smith, Claire, Gueorguieva, Ivelina, Miles, Colin, Guba, Susan C., Desaiah, Durisala, Estrem, Shawn T., Lahn, Michael M., Wick, Wolfgang
Publicado en Int J Mol Sci (2017)

A Randomized Phase III Study of Abemaciclib Versus Erlotinib in Patients with Stage IV Non-small Cell Lung Cancer With a Detectable KRAS Mutation Who Failed Prior Platinum-Based Th...

por Goldman, Jonathan W., Mazieres, Julien, Barlesi, Fabrice, Dragnev, Konstantin H., Koczywas, Marianna, Göskel, Tuncay, Cortot, Alexis B., Girard, Nicolas, Wesseler, Claas, Bischoff, Helge, Nadal, Ernest, Park, Keunchil, Lu, Shun, Taus, Alvaro, Cobo, Manuel, Estrem, Shawn T., Wijayawardana, Sameera R., Turner, Kellie, Oakley, Gerard Joseph, Hurt, Karla C., Chiang, Alan Y., Hossain, Anwar M., John, William J., Paz-Ares, Luis
Publicado en Front Oncol (2020)

Genome of the Bacterium Streptococcus pneumoniae Strain R6

por Hoskins, JoAnn, Alborn, William E., Arnold, Jeffrey, Blaszczak, Larry C., Burgett, Stanley, DeHoff, Bradley S., Estrem, Shawn T., Fritz, Lori, Fu, Dong-Jing, Fuller, Wendy, Geringer, Chad, Gilmour, Raymond, Glass, Jennifer S., Khoja, Hamid, Kraft, Angelika R., Lagace, Robert E., LeBlanc, Donald J., Lee, Linda N., Lefkowitz, Elliot J., Lu, Jin, Matsushima, Patti, McAhren, Scott M., McHenney, Margaret, McLeaster, Kevin, Mundy, Christopher W., Nicas, Thalia I., Norris, Franklin H., O'Gara, MaryJeanne, Peery, Robert B., Robertson, Gregory T., Rockey, Pamela, Sun, Pei-Ming, Winkler, Malcolm E., Yang, Yong, Young-Bellido, Michelle, Zhao, Genshi, Zook, Christopher A., Baltz, Richard H., Jaskunas, S. Richard, Rosteck, Paul R., Skatrud, Paul L., Glass, John I.
Publicado 2001