Hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi as a target for structure-based inhibitor design: crystallization and inhibition studies with purine analogs.

Por Eakin, A E, Guerra, A, Focia, P J, Torres-Martinez, J, Craig, S P
Publicado em 1997

Serine proteases from nematode and protozoan parasites: isolation of sequence homologs using generic molecular probes.

Por Sakanari, J A, Staunton, C E, Eakin, A E, Craik, C S, McKerrow, J H
Publicado em 1989

Comparative complement selection in bacteria enables screening for lead compounds targeted to a purine salvage enzyme of parasites.

Por Eakin, A E, Nieves-Alicea, R, Tosado-Acevedo, R, Chin, M S, Wang, C C, Craig, S P
Publicado em 1995

Ternary complex structure of human HGPRTase, PRPP, Mg2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding.

Por Balendiran, G. K., Molina, J. A., Xu, Y., Torres-Martinez, J., Stevens, R., Focia, P. J., Eakin, A. E., Sacchettini, J. C., Craig, S. P.
Publicado em 1999