MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention

Por Tischner, Christin, Hofer, Annette, Wulff, Veronika, Stepek, Joanna, Dumitru, Iulia, Becker, Lore, Haack, Tobias, Kremer, Laura, Datta, Alexandre N., Sperl, Wolfgang, Floss, Thomas, Wurst, Wolfgang, Chrzanowska-Lightowlers, Zofia, De Angelis, Martin Hrabe, Klopstock, Thomas, Prokisch, Holger, Wenz, Tina
Publicado no Hum Mol Genet (2015)

MTO1-Deficient Mouse Model Mirrors the Human Phenotype Showing Complex I Defect and Cardiomyopathy

Por Becker, Lore, Kling, Eva, Schiller, Evelyn, Zeh, Ramona, Schrewe, Anja, Hölter, Sabine M., Mossbrugger, Ilona, Calzada-Wack, Julia, Strecker, Valentina, Wittig, Ilka, Dumitru, Iulia, Wenz, Tina, Bender, Andreas, Aichler, Michaela, Janik, Dirk, Neff, Frauke, Walch, Axel, Quintanilla-Fend, Leticia, Floss, Thomas, Bekeredjian, Raffi, Gailus-Durner, Valérie, Fuchs, Helmut, Wurst, Wolfgang, Meitinger, Thomas, Prokisch, Holger, de Angelis, Martin Hrabě, Klopstock, Thomas
Publicado no PLoS One (2014)