Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo

Autor Arreba-Tutusaus, P, Mack, TS, Bullinger, L, Schnöder, TM, Polanetzki, A, Weinert, S, Ballaschk, A, Wang, Z, Deshpande, AJ, Armstrong, SA, Döhner, K, Fischer, T, Heidel, FH
Vydáno v Leukemia (2015)

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia

Autor Chen, C.W., Koche, R.P., Sinha, A.U., Deshpande, A.J., Zhu, N., Eng, R., Doench, J.G., Xu, H., Chu, S.H., Qi, J., Wang, X., Delaney, C., Bernt, K.M., Root, D.E., Hahn, W.C., Bradner, J.E., Armstrong, S.A.
Vydáno v Nat Med (2015)