Sequencing Histone Modifying Enzymes Identifies UTX mutations in Acute Lymphoblastic Leukemia

Por Mar, BG, Bullinger, L, Basu, E, Schlis, K, Silverman, LB, Döhner, K, Armstrong, SA
Publicado no Leukemia (2012)

MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment

Por Stubbs, MC, Kim, YM, Krivtsov, AV, Wright, RD, Feng, Z, Agarwal, J, Kung, AL, Armstrong, SA
Publicado em 2007

Impact of FLT3-ITD location on sensitivity to TKI-therapy in vitro and in vivo

Por Arreba-Tutusaus, P, Mack, TS, Bullinger, L, Schnöder, TM, Polanetzki, A, Weinert, S, Ballaschk, A, Wang, Z, Deshpande, AJ, Armstrong, SA, Döhner, K, Fischer, T, Heidel, FH
Publicado no Leukemia (2015)

DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia

Por Chen, C.W., Koche, R.P., Sinha, A.U., Deshpande, A.J., Zhu, N., Eng, R., Doench, J.G., Xu, H., Chu, S.H., Qi, J., Wang, X., Delaney, C., Bernt, K.M., Root, D.E., Hahn, W.C., Bradner, J.E., Armstrong, S.A.
Publicado no Nat Med (2015)