STAT3 as a mediator of BCR-ABL1-independent resistance in chronic myeloid leukemia

Por Eiring, A M, Kraft, I L, Page, B D, O'Hare, T, Gunning, P T, Deininger, M W
Publicado no Leukemia Suppl (2014)

Extreme mutational selectivity of axitinib limits its potential use as a targeted therapeutic for BCR-ABL1-positive leukemia

Por Zabriskie, M S, Eide, C A, Yan, D, Vellore, N A, Pomicter, A D, Savage, S L, Druker, B J, Deininger, M W, O'Hare, T
Publicado no Leukemia (2016)

A role for FOXO1 in BCR–ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia

Por Wagle, M, Eiring, A M, Wongchenko, M, Lu, S, Guan, Y, Wang, Y, Lackner, M, Amler, L, Hampton, G, Deininger, M W, O'Hare, T, Yan, Y
Publicado no Leukemia (2016)

Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo

Por Bright, S A, McElligott, A M, O'Connell, J W, O'Connor, L, Carroll, P, Campiani, G, Deininger, M W, Conneally, E, Lawler, M, Williams, D C, Zisterer, D M
Publicado em 2010

HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymp...

Por Tharkar-Promod, S, Johnson, D P, Bennett, S E, Dennis, E M, Banowsky, B G, Jones, S S, Shearstone, J R, Quayle, S N, Min, C, Jarpe, M, Mosbruger, T, Pomicter, A D, Miles, R R, Chen, W Y, Bhalla, K N, Zweidler-McKay, P A, Shrieve, D C, Deininger, M W, Chandrasekharan, M B, Bhaskara, S
Publicado no Leukemia (2018)

A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias

Por Cortes, J.E., Kim, D.-W., Pinilla-Ibarz, J., le Coutre, P., Paquette, R., Chuah, C., Nicolini, F.E., Apperley, J.F., Khoury, H.J., Talpaz, M., DiPersio, J., DeAngelo, D.J., Abruzzese, E., Rea, D., Baccarani, M., Müller, M.C., Gambacorti-Passerini, C., Wong, S., Lustgarten, S., Rivera, V.M., Clackson, T., Turner, C.D., Haluska, F.G., Guilhot, F., Deininger, M.W., Hochhaus, A., Hughes, T., Goldman, J.M., Shah, N.P., Kantarjian, H.
Publicado em 2013