Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

door Deegan, Tom D, Yeeles, Joseph TP, Diffley, John FX
Gepubliceerd in EMBO J (2016)

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

door Deegan, Tom D, Mukherjee, Progya P, Fujisawa, Ryo, Polo Rivera, Cristian, Labib, Karim
Gepubliceerd in eLife (2020)

Regulated Eukaryotic DNA Replication Origin Firing with Purified Proteins

door Yeeles, Joseph T.P., Deegan, Tom D., Janska, Agnieszka, Early, Anne, Diffley, John F. X.
Gepubliceerd in Nature (2015)

Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes

door Deegan, Tom D., Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T.P., Labib, Karim P.M.
Gepubliceerd in Mol Cell (2019)

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease

door Canal, Berta, Fujisawa, Ryo, McClure, Allison W., Deegan, Tom D., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S., Bertolin, Agustina P., Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F.X.
Gepubliceerd in Biochem J (2021)

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

door Canal, Berta, McClure, Allison W., Curran, Joseph F., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P., Milligan, Jennifer C., Basu, Souradeep, Drury, Lucy S., Deegan, Tom D., Fujisawa, Ryo, Roberts, Emma L., Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F.X.
Gepubliceerd in Biochem J (2021)