Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

le Deegan, Tom D, Yeeles, Joseph TP, Diffley, John FX
Foilsithe in EMBO J (2016)

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

le Deegan, Tom D, Mukherjee, Progya P, Fujisawa, Ryo, Polo Rivera, Cristian, Labib, Karim
Foilsithe in eLife (2020)

Regulated Eukaryotic DNA Replication Origin Firing with Purified Proteins

le Yeeles, Joseph T.P., Deegan, Tom D., Janska, Agnieszka, Early, Anne, Diffley, John F. X.
Foilsithe in Nature (2015)

Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes

le Deegan, Tom D., Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T.P., Labib, Karim P.M.
Foilsithe in Mol Cell (2019)

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease

le Canal, Berta, Fujisawa, Ryo, McClure, Allison W., Deegan, Tom D., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S., Bertolin, Agustina P., Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F.X.
Foilsithe in Biochem J (2021)

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

le Canal, Berta, McClure, Allison W., Curran, Joseph F., Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P., Milligan, Jennifer C., Basu, Souradeep, Drury, Lucy S., Deegan, Tom D., Fujisawa, Ryo, Roberts, Emma L., Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F.X.
Foilsithe in Biochem J (2021)