Chemoenzymatic Asymmetric Synthesis of Pregabalin Precursors via Asymmetric Bioreduction of β-Cyanoacrylate Esters Using Ene-Reductases

by Winkler, Christoph K., Clay, Dorina, Davies, Simon, O’Neill, Pat, McDaid, Paul, Debarge, Sebastien, Steflik, Jeremy, Karmilowicz, Mike, Wong, John W., Faber, Kurt
Published 2013

Nitrile as Activating Group in the Asymmetric Bioreduction of β-Cyanoacrylic Acids Catalyzed by Ene-Reductases

by Winkler, Christoph K, Clay, Dorina, Turrini, Nikolaus G, Lechner, Horst, Kroutil, Wolfgang, Davies, Simon, Debarge, Sebastien, O'Neill, Pat, Steflik, Jeremy, Karmilowicz, Mike, Wong, John W, Faber, Kurt
Published in Adv Synth Catal (2014)