Receptor heteromerization and drug discovery

Por Rozenfeld, Raphael, Devi, Lakshmi A.
Publicado em 2010

Receptor heterodimerization leads to a switch in signaling: β-arrestin2-mediated ERK activation by μ-δ opioid receptor heterodimers

Por Rozenfeld, Raphael, Devi, Lakshmi A.
Publicado em 2007

Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets

Por Williams, Dumaine, Devi, Lakshmi A.
Publicado em 2010

Regulation of CB(1) cannabinoid receptor trafficking by the adaptor protein AP-3

Por Rozenfeld, Raphael, Devi, Lakshmi A.
Publicado em 2008

Exploring a role for heteromerization in GPCR signalling specificity

Por ROZENFELD, Raphael, DEVI, Lakshmi A.
Publicado em 2010

Grand Opening of Structure-Guided Design for Novel Opioids

Por Filizola, Marta, Devi, Lakshmi A.
Publicado em 2012

How opioid drugs bind to receptors

Por Filizola, Marta, Devi, Lakshmi A.
Publicado em 2012

G-protein-coupled receptor heterodimerization modulates receptor function

Por Jordan, Bryen A., Devi, Lakshmi A.
Publicado em 1999

The Highs and Lows of Cannabinoid Receptor Expression in Disease: Mechanisms and Their Therapeutic Implications

Por Miller, Lydia K., Devi, Lakshmi A.
Publicado em 2011

Functional Relevance of μ-δ Opioid Receptor Heteromerization: A Role in Novel Signaling and Implications for the Treatment of Addiction Disorders

Por Stockton, Steven D., Devi, Lakshmi A.
Publicado em 2011

An Integrated Quantitative Proteomics and Systems Biology Approach to Explore Synaptic Protein Profile Changes During Morphine Exposure

Por Stockton, Steven D, Devi, Lakshmi A
Publicado em 2014

Advancements in therapeutically targeting orphan GPCRs

Por Stockert, Jennifer A., Devi, Lakshmi A.
Publicado no Front Pharmacol (2015)

Orphan neuropeptides and receptors: Novel therapeutic targets

Por Fricker, Lloyd D., Devi, Lakshmi A.
Publicado no Pharmacol Ther (2017)

μ opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis

Por Rios, Carl, Gomes, Ivone, Devi, Lakshmi A
Publicado em 2006

Cannabinoid-opioid interactions during neuropathic pain and analgesia

Por Bushlin, Ittai, Rozenfeld, Raphael, Devi, Lakshmi A
Publicado em 2009

Potentiation of μ–opioid receptor–mediated signaling by ketamine

Por Gupta, Achla, Devi, Lakshmi A., Gomes, Ivone
Publicado em 2011

G-Protein-Coupled Heteromers: Regulation in Disease

Por Gomes, Ivone, Gupta, Achla, Devi, Lakshmi A.
Publicado em 2013

Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR Review 10

Por Fujita, Wakako, Gomes, Ivone, Devi, Lakshmi A
Publicado no Br J Pharmacol (2014)

Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities

Por Fujita, Wakako, Gomes, Ivone, Devi, Lakshmi A
Publicado no Br J Pharmacol (2015)

Detection of Receptor Heteromerization Using In Situ Proximity Ligation Assay

Por Gomes, Ivone, Sierra, Salvador, Devi, Lakshmi A.
Publicado no Curr Protoc Pharmacol (2016)