Phenotypic assays in yeast and zebrafish reveal drugs that rescue ATP13A2 deficiency

gan Heins-Marroquin, Ursula, Jung, Paul P, Cordero-Maldonado, Maria Lorena, Crawford, Alexander D, Linster, Carole L
Cyhoeddwyd yn Brain Commun (2019)

Evaluation of 14 Organic Solvents and Carriers for Screening Applications in Zebrafish Embryos and Larvae

gan Maes, Jan, Verlooy, Lien, Buenafe, Olivia E., de Witte, Peter A. M., Esguerra, Camila V., Crawford, Alexander D.
Cyhoeddwyd 2012

CaSiAn: a Calcium Signaling Analyzer tool

gan Moein, Mahsa, Grzyb, Kamil, Gonçalves Martins, Teresa, Komoto, Shinya, Peri, Francesca, Crawford, Alexander D, Fouquier d’Herouel, Aymeric, Skupin, Alexander
Cyhoeddwyd yn Bioinformatics (2018)

Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine

gan Zhang, Yifan, Kecskés, Angéla, Copmans, Daniëlle, Langlois, Mélanie, Crawford, Alexander D., Ceulemans, Berten, Lagae, Lieven, de Witte, Peter A. M., Esguerra, Camila V.
Cyhoeddwyd yn PLoS One (2015)

Zebrafish Bioassay-Guided Natural Product Discovery: Isolation of Angiogenesis Inhibitors from East African Medicinal Plants

gan Crawford, Alexander D., Liekens, Sandra, Kamuhabwa, Appolinary R., Maes, Jan, Munck, Sebastian, Busson, Roger, Rozenski, Jef, Esguerra, Camila V., de Witte, Peter A. M.
Cyhoeddwyd 2011

Validation of the Zebrafish Pentylenetetrazol Seizure Model: Locomotor versus Electrographic Responses to Antiepileptic Drugs

gan Afrikanova, Tatiana, Serruys, Ann-Sophie K., Buenafe, Olivia E. M., Clinckers, Ralph, Smolders, Ilse, de Witte, Peter A. M., Crawford, Alexander D., Esguerra, Camila V.
Cyhoeddwyd 2013

Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites

gan Cordero-Maldonado, María Lorena, Siverio-Mota, Dany, Vicet-Muro, Liliana, Wilches-Arizábala, Isabel María, Esguerra, Camila V., de Witte, Peter A. M., Crawford, Alexander D.
Cyhoeddwyd 2013

Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models

gan Buenafe, Olivia Erin, Orellana-Paucar, Adriana, Maes, Jan, Huang, Hao, Ying, Xuhui, De Borggraeve, Wim, Crawford, Alexander D., Luyten, Walter, Esguerra, Camila V., de Witte, Peter
Cyhoeddwyd 2013

Zebrafish-based identification of the antiseizure nucleoside inosine from the marine diatom Skeletonema marinoi

gan Brillatz, Théo, Lauritano, Chiara, Jacmin, Maxime, Khamma, Supitcha, Marcourt, Laurence, Righi, Davide, Romano, Giovanna, Esposito, Francesco, Ianora, Adrianna, Queiroz, Emerson F., Wolfender, Jean-Luc, Crawford, Alexander D.
Cyhoeddwyd yn PLoS One (2018)

Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B

gan Copmans, Daniëlle, Kildgaard, Sara, Rasmussen, Silas A., Ślęzak, Monika, Dirkx, Nina, Partoens, Michèle, Esguerra, Camila V., Crawford, Alexander D., Larsen, Thomas O., de Witte, Peter A. M.
Cyhoeddwyd yn Mar Drugs (2019)

A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling

gan Gebruers, Evelien, Cordero-Maldonado, María Lorena, Gray, Alexander I., Clements, Carol, Harvey, Alan L., Edrada-Ebel, Ruangelie, de Witte, Peter A. M., Crawford, Alexander D., Esguerra, Camila V.
Cyhoeddwyd 2013

Deep learning image recognition enables efficient genome editing in zebrafish by automated injections

gan Cordero-Maldonado, Maria Lorena, Perathoner, Simon, van der Kolk, Kees-Jan, Boland, Ralf, Heins-Marroquin, Ursula, Spaink, Herman P., Meijer, Annemarie H., Crawford, Alexander D., de Sonneville, Jan
Cyhoeddwyd yn PLoS One (2019)

l-Isoaspartyl Methyltransferase Deficiency in Zebrafish Leads to Impaired Calcium Signaling in the Brain

gan Soliman, Remon, Cordero-Maldonado, Maria Lorena, Martins, Teresa G., Moein, Mahsa, Conrotte, Jean-François, Warmack, Rebeccah A., Skupin, Alexander, Crawford, Alexander D., Clarke, Steven G., Linster, Carole L.
Cyhoeddwyd yn Front Genet (2021)

2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes

gan Carballeira, Néstor M., Bwalya, Angela Gono, Itoe, Maurice Ayamba, Andricopulo, Adriano D., Cordero-Maldonado, María Lorena, Kaiser, Marcel, Mota, Maria M., Crawford, Alexander D., Guido, Rafael V. C., Tasdemir, Deniz
Cyhoeddwyd 2014

Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products

gan Bohni, Nadine, Cordero-Maldonado, María Lorena, Maes, Jan, Siverio-Mota, Dany, Marcourt, Laurence, Munck, Sebastian, Kamuhabwa, Appolinary R., Moshi, Mainen J., Esguerra, Camila V., de Witte, Peter A. M., Crawford, Alexander D., Wolfender, Jean-Luc
Cyhoeddwyd 2013

Potential of Lichen Secondary Metabolites against Plasmodium Liver Stage Parasites with FAS-II as the Potential Target

gan Lauinger, Ina L., Vivas, Livia, Perozzo, Remo, Stairiker, Christopher, Tarun, Alice, Zloh, Mire, Zhang, Xujie, Xu, Hua, Tonge, Peter J., Franzblau, Scott G., Pham, Duc-Hung, Esguerra, Camila V., Crawford, Alexander D., Maes, Louis, Tasdemir, Deniz
Cyhoeddwyd 2013

De Novo Loss-of-Function Mutations in CHD2 Cause a Fever-Sensitive Myoclonic Epileptic Encephalopathy Sharing Features with Dravet Syndrome

gan Suls, Arvid, Jaehn, Johanna A., Kecskés, Angela, Weber, Yvonne, Weckhuysen, Sarah, Craiu, Dana C., Siekierska, Aleksandra, Djémié, Tania, Afrikanova, Tatiana, Gormley, Padhraig, von Spiczak, Sarah, Kluger, Gerhard, Iliescu, Catrinel M., Talvik, Tiina, Talvik, Inga, Meral, Cihan, Caglayan, Hande S., Giraldez, Beatriz G., Serratosa, José, Lemke, Johannes R., Hoffman-Zacharska, Dorota, Szczepanik, Elzbieta, Barisic, Nina, Komarek, Vladimir, Hjalgrim, Helle, Møller, Rikke S., Linnankivi, Tarja, Dimova, Petia, Striano, Pasquale, Zara, Federico, Marini, Carla, Guerrini, Renzo, Depienne, Christel, Baulac, Stéphanie, Kuhlenbäumer, Gregor, Crawford, Alexander D., Lehesjoki, Anna-Elina, de Witte, Peter A.M., Palotie, Aarno, Lerche, Holger, Esguerra, Camila V., De Jonghe, Peter, Helbig, Ingo
Cyhoeddwyd 2013

CHD2 variants are a risk factor for photosensitivity in epilepsy

gan Galizia, Elizabeth C., Myers, Candace T., Leu, Costin, de Kovel, Carolien G. F., Afrikanova, Tatiana, Cordero-Maldonado, Maria Lorena, Martins, Teresa G., Jacmin, Maxime, Drury, Suzanne, Krishna Chinthapalli, V., Muhle, Hiltrud, Pendziwiat, Manuela, Sander, Thomas, Ruppert, Ann-Kathrin, Møller, Rikke S., Thiele, Holger, Krause, Roland, Schubert, Julian, Lehesjoki, Anna-Elina, Nürnberg, Peter, Lerche, Holger, Palotie, Aarno, Coppola, Antonietta, Striano, Salvatore, Gaudio, Luigi Del, Boustred, Christopher, Schneider, Amy L., Lench, Nicholas, Jocic-Jakubi, Bosanka, Covanis, Athanasios, Capovilla, Giuseppe, Veggiotti, Pierangelo, Piccioli, Marta, Parisi, Pasquale, Cantonetti, Laura, Sadleir, Lynette G., Mullen, Saul A., Berkovic, Samuel F., Stephani, Ulrich, Helbig, Ingo, Crawford, Alexander D., Esguerra, Camila V., Kasteleijn-Nolst Trenité, Dorothee G. A., Koeleman, Bobby P. C., Mefford, Heather C., Scheffer, Ingrid E., Sisodiya, Sanjay M.
Cyhoeddwyd yn Brain (2015)