Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice

por Götzl, Julia K., Colombo, Alessio-Vittorio, Fellerer, Katrin, Reifschneider, Anika, Werner, Georg, Tahirovic, Sabina, Haass, Christian, Capell, Anja
Publicado en Mol Neurodegener (2018)

Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

por Kuhn, Peer-Hendrik, Colombo, Alessio Vittorio, Schusser, Benjamin, Dreymueller, Daniela, Wetzel, Sebastian, Schepers, Ute, Herber, Julia, Ludwig, Andreas, Kremmer, Elisabeth, Montag, Dirk, Müller, Ulrike, Schweizer, Michaela, Saftig, Paul, Bräse, Stefan, Lichtenthaler, Stefan F
Publicado en eLife (2016)

Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

por Sebastian Monasor, Laura, Müller, Stephan A, Colombo, Alessio Vittorio, Tanrioever, Gaye, König, Jasmin, Roth, Stefan, Liesz, Arthur, Berghofer, Anna, Piechotta, Anke, Prestel, Matthias, Saito, Takashi, Saido, Takaomi C, Herms, Jochen, Willem, Michael, Haass, Christian, Lichtenthaler, Stefan F, Tahirovic, Sabina
Publicado en eLife (2020)

Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism

por Götzl, Julia K, Brendel, Matthias, Werner, Georg, Parhizkar, Samira, Sebastian Monasor, Laura, Kleinberger, Gernot, Colombo, Alessio‐Vittorio, Deussing, Maximilian, Wagner, Matias, Winkelmann, Juliane, Diehl‐Schmid, Janine, Levin, Johannes, Fellerer, Katrin, Reifschneider, Anika, Bultmann, Sebastian, Bartenstein, Peter, Rominger, Axel, Tahirovic, Sabina, Smith, Scott T, Madore, Charlotte, Butovsky, Oleg, Capell, Anja, Haass, Christian
Publicado en EMBO Mol Med (2019)

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

por Colombo, Alessio Vittorio, Sadler, Rebecca Katie, Llovera, Gemma, Singh, Vikramjeet, Roth, Stefan, Heindl, Steffanie, Sebastian Monasor, Laura, Verhoeven, Aswin, Peters, Finn, Parhizkar, Samira, Kamp, Frits, Gomez de Aguero, Mercedes, MacPherson, Andrew J, Winkler, Edith, Herms, Jochen, Benakis, Corinne, Dichgans, Martin, Steiner, Harald, Giera, Martin, Haass, Christian, Tahirovic, Sabina, Liesz, Arthur
Publicado en eLife (2021)