Anti-HER2 vaccines: new prospects for breast cancer therapy

per Ladjemi, Maha Zohra, Jacot, William, Chardès, Thierry, Pèlegrin, André, Navarro-Teulon, Isabelle
Publicat 2010

Biasing human epidermal growth factor receptor 4 (HER4) tyrosine kinase signaling with antibodies: Induction of cell death by antibody‐dependent HER4 intracellular domain trafficki...

per Lanotte, Romain, Garambois, Véronique, Gaborit, Nadège, Larbouret, Christel, Musnier, Astrid, Martineau, Pierre, Pèlegrin, André, Chardès, Thierry
Publicat a Cancer Sci (2020)

The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation

per Le Clorennec, Christophe, Lazrek, Yassamine, Dubreuil, Olivier, Larbouret, Christel, Poul, Marie-Alix, Mondon, Philippe, Melino, Gerry, Pèlegrin, André, Chardès, Thierry
Publicat a Oncotarget (2016)

Monoclonal Antibody 667 Recognizes the Variable Region A Motif of the Ecotropic Retrovirus CasBrE Envelope Glycoprotein and Inhibits Env Binding to the Viral Receptor

per Dreja, Hanna, Gros, Laurent, Villard, Sylvie, Bachrach, Estanislao, Oates, Anna, Granier, Claude, Chardes, Thierry, Mani, Jean-Claude, Piechaczyk, Marc, Pelegrin, Mireia
Publicat 2003

In Pancreatic Carcinoma, Dual EGFR/HER2 Targeting with Cetuximab/Trastuzumab Is More Effective than Treatment with Trastuzumab/Erlotinib or Lapatinib Alone: Implication of Receptor...

per Larbouret, Christel, Gaborit, Nadège, Chardès, Thierry, Coelho, Mickaël, Campigna, Emmanuelle, Bascoul-Mollevi, Caroline, Mach, Jean-Pierre, Azria, David, Robert, Bruno, Pèlegrin, André
Publicat 2012

Time-resolved Fluorescence Resonance Energy Transfer (TR-FRET) to Analyze the Disruption of EGFR/HER2 Dimers: A NEW METHOD TO EVALUATE THE EFFICIENCY OF TARGETED THERAPY USING MONO...

per Gaborit, Nadège, Larbouret, Christel, Vallaghe, Julie, Peyrusson, Frédéric, Bascoul-Mollevi, Caroline, Crapez, Evelyne, Azria, David, Chardès, Thierry, Poul, Marie-Alix, Mathis, Gérard, Bazin, Hervé, Pèlegrin, André
Publicat 2011

ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells

per Le Clorennec, Christophe, Lazrek, Yassamine, Dubreuil, Olivier, Sampaio, Carla, Larbouret, Christel, Lanotte, Romain, Poul, Marie-Alix, Barret, Jean-Marc, Prost, Jean-François, Pèlegrin, André, Chardès, Thierry
Publicat a Cell Commun Signal (2019)

Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice

per Ladjemi, Maha Z, Chardes, Thierry, Corgnac, Stephanie, Garambois, Veronique, Morisseau, Sebastien, Robert, Bruno, Bascoul-Mollevi, Caroline, Ait Arsa, Imade, Jacot, William, Pouget, Jean-Pierre, Pelegrin, Andre, Navarro-Teulon, Isabelle
Publicat 2011

Preclinical validation of AXL receptor as a target for antibody-based pancreatic cancer immunotherapy

per Leconet, Wilhem, Larbouret, Christel, Chardès, Thierry, Thomas, Gaëlle, Neiveyans, Madeline, Busson, Muriel, Jarlier, Marta, Radosevic-Robin, Nina, Pugnière, Martine, Bernex, Florence, Penault-Llorca, Frédérique, Pasquet, Jean-Max, Pèlegrin, André, Robert, Bruno
Publicat a Oncogene (2014)

Anti-Müllerian hormone (AMH) autocrine signaling promotes survival and proliferation of ovarian cancer cells

per Chauvin, Maëva, Garambois, Véronique, Colombo, Pierre-Emmanuel, Chentouf, Myriam, Gros, Laurent, Brouillet, Jean-Paul, Robert, Bruno, Jarlier, Marta, Dumas, Karen, Martineau, Pierre, Navarro-Teulon, Isabelle, Pépin, David, Chardès, Thierry, Pèlegrin, André
Publicat a Sci Rep (2021)

The human Müllerian inhibiting substance type II receptor as immunotherapy target for ovarian cancer: Validation using the mAb 12G4

per Kersual, Nathalie, Garambois, Véronique, Chardès, Thierry, Pouget, Jean-Pierre, Salhi, Imed, Bascoul-Mollevi, Caroline, Bibeau, Frédéric, Busson, Muriel, Vié, Henri, Clémenceau, Béatrice, Behrens, Christian K, Estupina, Pauline, Pèlegrin, André, Navarro-Teulon, Isabelle
Publicat a MAbs (2014)

Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects

per Paillas, Salomé, Ladjohounlou, Riad, Lozza, Catherine, Pichard, Alexandre, Boudousq, Vincent, Jarlier, Marta, Sevestre, Samuel, Le Blay, Marion, Deshayes, Emmanuel, Sosabowski, Jane, Chardès, Thierry, Navarro-Teulon, Isabelle, Mairs, Robert J., Pouget, Jean-Pierre
Publicat a Antioxid Redox Signal (2016)

Examination of HER3 targeting in cancer using monoclonal antibodies

per Gaborit, Nadège, Abdul-Hai, Ali, Mancini, Maicol, Lindzen, Moshit, Lavi, Sara, Leitner, Orith, Mounier, Lucile, Chentouf, Myriam, Dunoyer, Sai, Ghosh, Manjusha, Larbouret, Christel, Chardès, Thierry, Bazin, Hervé, Pèlegrin, André, Sela, Michael, Yarden, Yosef
Publicat a Proc Natl Acad Sci U S A (2015)

Quantification of HER1, HER2 and HER3 by time-resolved Förster resonance energy transfer in FFPE triple-negative breast cancer samples

per Ho-Pun-Cheung, Alexandre, Bazin, Hervé, Boissière-Michot, Florence, Mollevi, Caroline, Simony-Lafontaine, Joëlle, Landas, Emeline, Bleuse, Jean-Pierre, Chardès, Thierry, Prost, Jean-François, Pèlegrin, André, Jacot, William, Mathis, Gérard, Lopez-Crapez, Evelyne
Publicat a Br J Cancer (2019)

A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector funct...

per Neiveyans, Madeline, Melhem, Rana, Arnoult, Christophe, Bourquard, Thomas, Jarlier, Marta, Busson, Muriel, Laroche, Adrien, Cerutti, Martine, Pugnière, Martine, Ternant, David, Gaborit, Nadège, Chardès, Thierry, Poupon, Anne, Gouilleux-Gruart, Valérie, Pèlegrin, Andre, Poul, Marie-Alix
Publicat a MAbs (2019)

Anti-HER3 Domain 1 and 3 Antibodies Reduce Tumor Growth by Hindering HER2/HER3 Dimerization and AKT-Induced MDM2, XIAP, and FoxO1 Phosphorylation

per Lazrek, Yassamine, Dubreuil, Olivier, Garambois, Véronique, Gaborit, Nadège, Larbouret, Christel, Le Clorennec, Christophe, Thomas, Gaelle, Leconet, Wilhem, Jarlier, Marta, Pugnière, Martine, Vié, Nadia, Robert, Bruno, Monnet, Céline, Bouayadi, Khalil, Kharrat, Hakim, Mondon, Philippe, Pèlegrin, André, Chardès, Thierry
Publicat 2013

Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival

per Chauvin, Maëva, Garambois, Véronique, Choblet, Sylvie, Colombo, Pierre-Emmanuel, Chentouf, Myriam, Gros, Laurent, De Brauwere, David-Paul, Duonor-Cerutti, Martine, Dumas, Karen, Robert, Bruno, Jarlier, Marta, Martineau, Pierre, Navarro-Teulon, Isabelle, Pépin, David, Chardès, Thierry, Pèlegrin, André
Publicat a Int J Oncol (2021)

Anti-tumoral activity of the Pan-HER (Sym013) antibody mixture in gemcitabine-resistant pancreatic cancer models

per Rabia, Emilia, Garambois, Véronique, Hubert, Julie, Bruciamacchie, Marine, Pirot, Nelly, Delpech, Hélène, Broyon, Morgane, Theillet, Charles, Colombo, Pierre-Emmanuel, Vie, Nadia, Tosi, Diego, Gongora, Celine, Khellaf, Lakhdar, Jarlier, Marta, Radosevic-Robin, Nina, Chardès, Thierry, Pèlegrin, André, Larbouret, Christel
Publicat a MAbs (2021)

A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment

per Alcaraz, Lindsay B, Mallavialle, Aude, David, Timothée, Derocq, Danielle, Delolme, Frédéric, Dieryckx, Cindy, Mollevi, Caroline, Boissière-Michot, Florence, Simony-Lafontaine, Joëlle, Du Manoir, Stanislas, Huesgen, Pitter F., Overall, Christopher M., Tartare-Deckert, Sophie, Jacot, William, Chardès, Thierry, Guiu, Séverine, Roger, Pascal, Reinheckel, Thomas, Moali, Catherine, Liaudet-Coopman, Emmanuelle
Publicat a Theranostics (2021)

The anti-tumor efficacy of 3C23K, a glyco-engineered humanized anti-MISRII antibody, in an ovarian cancer model is mainly mediated by engagement of immune effector cells

per Estupina, Pauline, Fontayne, Alexandre, Barret, Jean-Marc, Kersual, Nathalie, Dubreuil, Olivier, Le Blay, Marion, Pichard, Alexandre, Jarlier, Marta, Pugnière, Martine, Chauvin, Maëva, Chardès, Thierry, Pouget, Jean-Pierre, Deshayes, Emmanuel, Rossignol, Alexis, Abache, Toufik, de Romeuf, Christophe, Terrier, Aurélie, Verhaeghe, Lucie, Gaucher, Christine, Prost, Jean-François, Pèlegrin, André, Navarro-Teulon, Isabelle
Publicat a Oncotarget (2017)