A critical analysis of codon optimization in human therapeutics

Por Mauro, Vincent P., Chappell, Stephen A.
Publicado no Trends Mol Med (2014)

A 9-nt segment of a cellular mRNA can function as an internal ribosome entry site (IRES) and when present in linked multiple copies greatly enhances IRES activity

Por Chappell, Stephen A., Edelman, Gerald M., Mauro, Vincent P.
Publicado em 2000

Biochemical and functional analysis of a 9-nt RNA sequence that affects translation efficiency in eukaryotic cells

Por Chappell, Stephen A., Edelman, Gerald M., Mauro, Vincent P.
Publicado em 2004

Ribosomal tethering and clustering as mechanisms for translation initiation

Por Chappell, Stephen A., Edelman, Gerald M., Mauro, Vincent P.
Publicado em 2006

Ribosomal shunting mediated by a translational enhancer element that base pairs to 18S rRNA

Por Chappell, Stephen A., Dresios, John, Edelman, Gerald M., Mauro, Vincent P.
Publicado em 2006

Identification of two short internal ribosome entry sites selected from libraries of random oligonucleotides

Por Owens, Geoffrey C., Chappell, Stephen A., Mauro, Vincent P., Edelman, Gerald M.
Publicado em 2001

Internal initiation of translation of five dendritically localized neuronal mRNAs

Por Pinkstaff, Jason K., Chappell, Stephen A., Mauro, Vincent P., Edelman, Gerald M., Krushel, Les A.
Publicado em 2001

c-Myc Protein Synthesis Is Initiated from the Internal Ribosome Entry Segment during Apoptosis

Por Stoneley, Mark, Chappell, Stephen A., Jopling, Catherine L., Dickens, Martin, MacFarlane, Marion, Willis, Anne E.
Publicado em 2000